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未经治疗的成人膀胱外翻中的移行细胞癌:一例罕见病例报告。

Transitional cell carcinoma in untreated adult bladder exstrophy: A rare case report.

作者信息

Handoko Richardo R, Ismy Jufriady, Badiri Istanul

机构信息

Department of Urology, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia.

Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala, Zainoel Abidin Hospital, Banda Aceh, Indonesia.

出版信息

Urol Case Rep. 2022 Jan 17;42:102004. doi: 10.1016/j.eucr.2022.102004. eCollection 2022 May.

DOI:10.1016/j.eucr.2022.102004
PMID:35106286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8784629/
Abstract

Untreated adult bladder exstrophy is a very rare entity and has a higher risk of developing bladder cancer. A 41-year old man with acute kidney injury and bilateral hydronephrosis was consulted to Urology Division. Examination revealed bladder exstrophy with suspected malignancy. The incisional biopsy result showed transitional cell carcinoma which is the most common bladder cancer, but extremely rare in bladder exstrophy. Radical cystectomy and urinary diversion with double-barrel ureterocutaneostomy were conducted. Abdominal defect was closed with surgical mesh application and rotational skin flap. The patient was well recovered with improved quality of life.

摘要

未经治疗的成人膀胱外翻是一种非常罕见的病症,患膀胱癌的风险更高。一名患有急性肾损伤和双侧肾积水的41岁男性被转诊至泌尿外科。检查发现膀胱外翻并疑似恶性肿瘤。切开活检结果显示为移行细胞癌,这是最常见的膀胱癌类型,但在膀胱外翻中极为罕见。进行了根治性膀胱切除术和双管输尿管皮肤造口术的尿流改道。使用手术网片和旋转皮瓣封闭腹部缺损。患者恢复良好,生活质量得到改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/8784629/af4a82da361f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/8784629/0c45c07ff245/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/8784629/f0c38f2f6466/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/8784629/af4a82da361f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/8784629/0c45c07ff245/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/8784629/f0c38f2f6466/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/8784629/af4a82da361f/gr3.jpg

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本文引用的文献

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Management of Untreated Classical Bladder Exstrophy in Adults: A Single-Institutional Experience.成人未经治疗的典型膀胱外翻的管理:单机构经验
Urology. 2020 Dec;146:293-298. doi: 10.1016/j.urology.2020.09.009. Epub 2020 Sep 20.
2
Urological, Sexual, and Quality of Life Evaluation of Adult Patients With Exstrophy-Epispadias Complex: Long-term Results From a Dutch Cohort.成人膀胱外翻-尿道上裂患者的泌尿科、性功能和生活质量评估:荷兰队列的长期结果。
Urology. 2020 Feb;136:272-277. doi: 10.1016/j.urology.2019.10.011. Epub 2019 Nov 4.
3
Invasive Squamous Carcinoma and Adenocarcinoma of an Unreconstructed Exstrophic Bladder with HPV Infection.
未重建的膀胱外翻伴人乳头瘤病毒感染的浸润性鳞状细胞癌和腺癌。
Curr Urol. 2016 May;9(2):109-12. doi: 10.1159/000442863. Epub 2016 May 20.
4
Neoplasia in adult exstrophy patients.
BJU Int. 2001 May;87(7):623-8. doi: 10.1046/j.1464-410x.2001.02136.x.