Department of Surgical Oncology, Hiroshima University, Hiroshima, Japan.
Thorac Cancer. 2022 Mar;13(6):876-879. doi: 10.1111/1759-7714.14339. Epub 2022 Feb 1.
Most primary esophageal adenocarcinomas arise from the Barrett epithelium of the distal esophagus. Thus, cancer developing from the ectopic gastric mucosa (EGM) of the proximal esophagus is extremely rare. Furthermore, recurrent adenocarcinoma at the EGM has not been reported. Here, we describe adenocarcinoma originating from the EGM at the boundary of the cervical and thoracic esophagus that recurred twice at the same site within 40 months. This adenocarcinoma was treated throughout its course by three endoscopic submucosal dissections and a subsequent thoracoscopic esophagectomy. This is the first description of recurrent adenocarcinoma originating from the EGM of the proximal esophagus.
大多数原发性食管腺癌起源于远端食管的 Barrett 上皮。因此，起源于近端食管异位胃黏膜（EGM）的癌症极为罕见。此外，EGM 处的复发性腺癌尚未见报道。在此，我们描述了一例起源于颈段和胸段食管交界处 EGM 的腺癌，在 40 个月内同一部位复发两次。该腺癌在整个病程中通过 3 次内镜黏膜下剥离术和随后的胸腔镜食管切除术进行治疗。这是首例起源于近端食管 EGM 的复发性腺癌的描述。
