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Critical insights to COVID-19 disease and potential treatments using a systems analysis approach that integrates physiology, pharmacology, and clinical pharmacology.

作者信息

Martin Jennifer H, Head Richard J

机构信息

The University of Newcastle Hunter Medical Research Institute, New Lambton, New South Wales, Australia.

Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.

出版信息

Pharmacol Res Perspect. 2022 Feb;10(1):e00918. doi: 10.1002/prp2.918.

DOI:10.1002/prp2.918
PMID:35106934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8929325/
Abstract
摘要

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本文引用的文献

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Systems analysis shows that thermodynamic physiological and pharmacological fundamentals drive COVID-19 and response to treatment.系统分析表明，热力学生理和药理学基础驱动着 COVID-19 及其对治疗的反应。
Pharmacol Res Perspect. 2022 Feb;10(1):e00922. doi: 10.1002/prp2.922.
2
The interacting physiology of COVID-19 and the renin-angiotensin-aldosterone system: Key agents for treatment.新型冠状病毒肺炎与肾素-血管紧张素-醛固酮系统的相互作用生理学：治疗的关键药物。
Pharmacol Res Perspect. 2022 Feb;10(1):e00917. doi: 10.1002/prp2.917.
3
"LONG COVID"-A hypothesis for understanding the biological basis and pharmacological treatment strategy.“长新冠”-理解生物学基础和药物治疗策略的假说。
Pharmacol Res Perspect. 2022 Feb;10(1):e00911. doi: 10.1002/prp2.911.
4
Statin withdrawal and treating COVID-19 patients.他汀类药物停药与 COVID-19 患者的治疗。
Pharmacol Res Perspect. 2021 Dec;9(6):e00861. doi: 10.1002/prp2.861.
5
Did our pharmacological strategy for COVID-19 fail?我们针对新冠病毒病的药理学策略失败了吗？
Pharmacol Res Perspect. 2021 Dec;9(6):e00866. doi: 10.1002/prp2.866.
6
Obesity and COVID-19: renin-angiotensin as a mediator of morbidity and mortality.肥胖与2019冠状病毒病：肾素-血管紧张素作为发病和死亡的介质
Br J Nutr. 2022 May 14;127(9):1439-1440. doi: 10.1017/S0007114521001847. Epub 2021 Jun 3.
7
A pharmacological framework for integrating treating the host, drug repurposing and the damage response framework in COVID-19.在 COVID-19 中整合宿主治疗、药物重定位和损伤反应框架的药理学框架。
Br J Clin Pharmacol. 2021 Mar;87(3):875-885. doi: 10.1111/bcp.14551. Epub 2020 Nov 18.
8
Long covid: How to define it and how to manage it.长期新冠：如何定义及如何应对。
BMJ. 2020 Sep 7;370:m3489. doi: 10.1136/bmj.m3489.