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可卡因相关性颈脊髓梗死:病例报告并文献复习。

Cocaine-related cervical spinal cord infarction: a case report and review of the literature.

机构信息

Spinal Cord Unit, IRCCS S. Lucia Foundation, Via Ardeatina 306, 00179, Rome, Italy.

SPInal REhabilitation Lab (SPIRE), IRCCS Fondazione Santa Lucia, Rome, Italy.

出版信息

J Med Case Rep. 2022 Feb 2;16(1):59. doi: 10.1186/s13256-021-03223-4.

Abstract

STUDY DESIGN

Case report.

OBJECTIVES

To report a clinical case of spinal cord infarction due to cocaine use.

SETTING

Spinal Center, IRCCS Fondazione S. Lucia, Rome (Italy).

CASE PRESENTATION

Two days after recreational use of cocaine, a 27-year-old Caucasic man was admitted to the emergency department for acute cervical pain, weakness in all four limbs, and urinary retention. A cervical spinal magnetic resonance imaging scan, performed after 2 days, showed a "pencil-like" lesion extending from C4 to T1 metamer, compatible with acute ischemia in the anterior spinal artery territory. Other causes of vascular disorders, as well as inflammatory and infectious disorders were ruled out. At admission in our department, the patient had an incomplete tetraplegia at level C6, an indwelling catheter, and was unable to stand and walk. After 3 months of rehabilitation, he had an AIS score D tetraplegia at level C7, was able to stand and walk using parallel bars, and indwelling catheter was replaced by intermittent catheterization.

DISCUSSION AND CONCLUSIONS

The etiology of medullary infarction may remain unexplained in nearly 30-40% of cases. Even if rare, cocaine-induced ischemic myelopathy should be considered and ruled out in the differential diagnosis of any acute nontraumatic myelopathy, especially in young patients.

摘要

研究设计

病例报告。

目的

报告一例因可卡因使用导致的脊髓梗死的临床病例。

地点

罗马圣卢西亚基金会脊髓中心(意大利)。

病例介绍

一名 27 岁的白种男性,在吸食可卡因 2 天后因急性颈痛、四肢无力和尿潴留被收入急诊。2 天后进行的颈椎磁共振成像扫描显示,“铅笔状”病变从 C4 延伸至 T1 节段,符合脊髓前动脉区域的急性缺血。排除了其他血管疾病、炎症和感染性疾病的可能性。在我们科室入院时,患者 C6 水平不完全性四肢瘫痪,留置导尿管,无法站立和行走。经过 3 个月的康复治疗,他的 AIS 评分在 C7 水平为 D 级四肢瘫痪,能够使用平行杠站立和行走,留置导尿管已更换为间歇性导尿。

讨论和结论

近 30-40%的情况下,仍可能无法明确引起脊髓梗死的病因。即使罕见,也应考虑可卡因引起的缺血性脊髓病,并在任何急性非创伤性脊髓病的鉴别诊断中排除,尤其是在年轻患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/353f/8809035/d0bbb8f8cb2e/13256_2021_3223_Fig1_HTML.jpg

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