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年轻患者滥用冰毒致脊髓梗死。

Spinal cord infarction in a young patient with methamphetamine abuse.

机构信息

Medical, Hospital Seberang Jaya, Seberang Jaya, Pulau Pinang, Malaysia.

Medical, Hospital Seberang Jaya, Seberang Jaya, Pulau Pinang, Malaysia

出版信息

BMJ Case Rep. 2021 Mar 30;14(3):e241031. doi: 10.1136/bcr-2020-241031.

Abstract

We report a case of a 20-year-old man who was diagnosed with spontaneous spinal cord infarction after abusing methamphetamine for a year. He presented with sudden onset of bilateral upper and lower limb weakness. His MRI spine showed a long segment of high signal intensity seen predominantly in the anterior spinal cord from medulla to mid thoracic level as well as a pencil-like hyperintensity seen postcontrast suggestive of spinal cord ischaemia or infarct. Thus, he was empirically treated for presumed anterior spinal cord infarction. He then developed autonomic dysfunction and went into respiratory distress, which required invasive mechanical ventilation support. Subsequently, he developed cardiac arrythmia with supraventricular tachycardiac followed by asystole and succumbed to illness on day 9 despite maximal resuscitative efforts. This case report illustrates a rare spinal cord infarction caused by methamphetamine intoxication and the importance of identifying and treating it early.

摘要

我们报告了一例 20 岁的男性患者,该患者在滥用甲基苯丙胺一年后被诊断为自发性脊髓梗死。他表现为突然出现双侧上下肢无力。他的脊柱 MRI 显示长节段高信号强度,主要位于从延髓到胸中段的前脊髓,以及铅笔状的高信号强度,提示脊髓缺血或梗死。因此,他被经验性地治疗为疑似前脊髓梗死。随后,他出现自主神经功能障碍并出现呼吸窘迫,需要进行有创机械通气支持。随后,他出现室上性心动过速伴心律失常,随后出现心脏停搏,并在发病第 9 天尽管进行了最大程度的复苏努力仍死于疾病。本病例报告说明了一例由甲基苯丙胺中毒引起的罕见脊髓梗死,并强调了早期识别和治疗的重要性。

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