Nephrology, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal
Clínica Universitária de Nefrologia, Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal.
BMJ Case Rep. 2022 Feb 2;15(2):e246651. doi: 10.1136/bcr-2021-246651.
Immunoglobulin replacement therapy is an important therapeutic approach used in different diseases, such as immunodeficiency diseases. We report a case of a 19-year-old female patient with suspected common variable immunodeficiency who started replacement therapy with IgG. During the follow-up, she developed interstitial nephritis and the subsequent workup excluded other diseases or triggers except IgG therapy.
免疫球蛋白替代疗法是一种在不同疾病中使用的重要治疗方法,如免疫缺陷疾病。我们报告了一例 19 岁女性疑似普通变异性免疫缺陷患者,她开始接受 IgG 替代治疗。在随访期间,她发生了间质性肾炎,随后的检查排除了 IgG 治疗以外的其他疾病或诱因。