Dept of Neurology, North-Western State Medical University, Saint Petersburg, Russia.
Dept of Clinical Medicine, University of Bergen, Bergen, Norway.
Spinal Cord Ser Cases. 2022 Feb 2;8(1):16. doi: 10.1038/s41394-022-00484-z.
Retrospective cohort study.
To evaluate influence of age after traumatic spinal cord injury (TSCI).
13 specialized hospitals with neurosurgical departments of Saint Petersburg, Russia.
Charts of all patients admitted with TSCI to the city hospitals 2012-2016. Demographic and clinical characteristics, surgical interventions, complications, mortality rate, and hospital stays were recorded.
311 patients with TSCI were included. TSCI was more common in younger age. Mean age (SD) was 42.4 (16.8) years. Patients were divided into four age groups: 18-29, 30-44, 45-59 and ≥60 years. The group ≥60 years had the lowest percentage of concomitant traumatic brain injury (TBI), 25%, versus 43% in TSCI < 60 years, p < 0.05. Low falls were the most frequent cause in patients aged 60 years and older, and led to less severe neurological deficits (p < 0.05). Complications were most frequent in motor complete TSCI (AIS A and AIS B) and in persons with combined TSCI and TBI at older age. Total complication rate was 67% at the age of ≥60 years versus 38% <60 years in TSCI with TBI (p < 0.05). Respiratory complications occurred in 67% ≥45 years versus 45% <45 years, p < 0.05. In-hospital mortality rate after TSCI was higher in the oldest age group.
Respiratory complications are common and the in-hospital mortality is higher among elderly people. Older patients with TSCI and TBI are at high risk for complications.
回顾性队列研究。
评估创伤性脊髓损伤（TSCI）后年龄的影响。
俄罗斯圣彼得堡 13 家具有神经外科的专科医院。
对 2012 年至 2016 年在城市医院收治的所有 TSCI 患者的病历进行记录。记录人口统计学和临床特征、手术干预、并发症、死亡率和住院时间。
纳入 311 例 TSCI 患者。TSCI 在较年轻的年龄中更为常见。平均年龄（标准差）为 42.4（16.8）岁。患者分为四个年龄组：18-29 岁、30-44 岁、45-59 岁和≥60 岁。≥60 岁组合并创伤性脑损伤（TBI）的比例最低，为 25%，而＜60 岁组为 43%，p＜0.05。60 岁以上的患者最常见的原因是低坠伤，导致的神经功能缺损程度较轻（p＜0.05）。并发症在运动完全性 TSCI（AIS A 和 AIS B）和年龄较大的合并 TSCI 和 TBI 的患者中最为常见。≥60 岁患者的总并发症发生率为 67%，而 TBI 的＜60 岁患者为 38%（p＜0.05）。≥45 岁的患者中发生呼吸并发症的比例为 67%，而＜45 岁的患者为 45%，p＜0.05。TSCI 后住院死亡率在年龄最大的组中较高。
呼吸并发症常见，老年人的住院死亡率较高。年龄较大的 TSCI 和 TBI 患者并发症风险较高。
