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CD34染色助力诊断骨髓偶然发现的毛细血管瘤

CD 34 Staining to the Rescue in an Incidental Capillary Hemangioma of the Bone Marrow.

作者信息

Sharma Saniya, Jain Richa, Ahluwalia Jasmina

机构信息

Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Pediatric Hematology & Oncology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Surg Oncol. 2021 Dec;12(4):708-709. doi: 10.1007/s13193-021-01317-5. Epub 2021 Apr 16.

DOI:10.1007/s13193-021-01317-5
PMID:35110892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8763995/
Abstract

Intraosseous hemangiomas are extremely rare and benign neoplasms of vascular origin, usually occurring in adults and involving skull bones, vertebra, ribs, sternum, long bones, patella and clavicle. Iliac or pelvic bone involvement is extremely rare. Hemangiomas of the marrow spaces are extremely uncommon. We report this rare neoplasm in a child that was incidentally detected on bone marrow examination for thrombocytopenia which mimicked a metastatic deposit. However, immunostaining with CD34 was successful in characterizing this solid vascular lesion as capillary hemangioma. This report emphasizes the importance of correctly identifying this lesion with the help of simple CD34 immunostaining since no specific therapy is required.

摘要

骨内血管瘤是极为罕见的血管源性良性肿瘤,通常发生于成年人,累及颅骨、椎骨、肋骨、胸骨、长骨、髌骨和锁骨。累及髂骨或骨盆骨极为罕见。骨髓腔内血管瘤极其少见。我们报告了一名儿童中的这种罕见肿瘤,该肿瘤在因血小板减少症进行骨髓检查时偶然发现,类似转移性沉积物。然而,通过CD34免疫染色成功将这种实性血管病变特征化为毛细血管瘤。本报告强调了借助简单的CD34免疫染色正确识别该病变的重要性,因为无需特殊治疗。

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本文引用的文献

1
Hemangioma of the Ilium Simulating an Aggressive Bone Lesion on Imaging.髂骨血管瘤在影像学上模拟侵袭性骨病变
Radiol Case Rep. 2015 Dec 7;2(3):74. doi: 10.2484/rcr.2007.v2i3.74. eCollection 2007.
2
Intraosseous haemangioma of the ilium.髂骨骨内血管瘤
Pediatr Radiol. 2006 Jan;36(1):54-6. doi: 10.1007/s00247-005-0005-1. Epub 2005 Oct 25.
3
Hemangioma from head to toe: MR imaging with pathologic correlation.从头到脚的血管瘤:磁共振成像与病理对照
Radiographics. 2004 Mar-Apr;24(2):367-85. doi: 10.1148/rg.242035079.
4
Update on hemangiomas and vascular malformations.血管瘤与血管畸形的最新进展
Curr Opin Pediatr. 1999 Oct;11(5):457-63. doi: 10.1097/00008480-199910000-00015.