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Editorial: Amino Acid Transport and Metabolism During Homeostasis and Inflammation.

作者信息

Cibrian Danay, Baixauli Francesc, Palacin Manuel

机构信息

Vascular Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.

Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, Freiburg, Germany.

出版信息

Front Immunol. 2022 Jan 17;12:833258. doi: 10.3389/fimmu.2021.833258. eCollection 2021.

Abstract
摘要

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A guide to plasma membrane solute carrier proteins.
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First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors.
Invest New Drugs. 2020 Oct;38(5):1495-1506. doi: 10.1007/s10637-020-00924-3. Epub 2020 Mar 20.
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Targeting L-type amino acid transporter 1 in innate and adaptive T cells efficiently controls skin inflammation.
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Interleukin-18 up-regulates amino acid transporters and facilitates amino acid-induced mTORC1 activation in natural killer cells.
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Regulation of the Immune Response by the Aryl Hydrocarbon Receptor.
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Twenty-five years of mTOR: Uncovering the link from nutrients to growth.
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