Faculty of Health Sciences, International University Goražde, Bosnia and Herzegovina.
Pediatric Clinic, Clinical University Centre Sarajevo, Bosnia and Herzegovina.
Med Glas (Zenica). 2022 Feb 1;19(1):1-5. doi: 10.17392/1460-21.
Lenticulostriate vasculopathy (LSV) is a relatively common fi nding in routine cranial ultrasound examination that has been associated with many infectious and non-infectious conditions. The aim of this review was to provide a better understanding of LSV ultrasound fi nding, as well as the need for further laboratory and imaging examinations in infants. The most of the published studies represented small series, with few prospective long-term studies involving the control groups. Authors have mostly found an association between LSV, especially higher-grade (although there is no universally accepted classifi cation) with congenital cytomegalovirus (CMV) infection, classifying those children as at risk for sensorineural hearing loss. In contrast, some authors pointed out that LSV could be found relatively often, and believe that isolated LSV, especially lower-grade, is not predictive for an unfavourable outcome and a long-term prognosis. Therefore, although 35 years have passed since the first publication of LSV, there is still no consensus among experts on the clinical signifi cance of isolated LSV, but caution is certainly needed given the fact that most infants with congenital CMV are asymptomatic.
纹状体区血管病变（LSV）是常规头颅超声检查中较为常见的发现，与许多感染性和非感染性疾病有关。本综述的目的是更好地了解 LSV 的超声表现，以及婴儿进一步进行实验室和影像学检查的必要性。已发表的研究大多为小系列研究，涉及对照组的前瞻性长期研究较少。作者主要发现 LSV 与先天性巨细胞病毒（CMV）感染之间存在关联，尤其是较高等级（尽管目前尚无普遍接受的分类），将这些儿童归类为感觉神经性听力损失的风险。相比之下，一些作者指出，LSV 相对常见，并且认为孤立性 LSV，尤其是较低等级，不能预测不良结局和长期预后。因此，尽管 LSV 自首次发表以来已经过去了 35 年，但专家们对孤立性 LSV 的临床意义仍未达成共识，但鉴于大多数先天性 CMV 婴儿无症状，因此当然需要谨慎。
