Department of Internal Medicine, University General Hospital of Patras, Greece.
Department of General Surgery, University General Hospital of Patras, Greece.
Med Glas (Zenica). 2022 Feb 1;19(1):32-40. doi: 10.17392/1440-21.
Aim COVID-19 pandemic caused by SARS-CoV-2 is spreading throughout the world affecting both healthy individuals and people with underlying immune-deficiencies. People living with human immunodeficiency virus (HIV) consist a group multiply affected by this universal crisis. Methods Literature search aiming to identify relevant publications referring to the consequences of the COVID-19 pandemic in HIV infected population. Results A body of literature is rapidly growing in regard to epidemiological data, the interaction between HIV and SARS-CoV-2, and clinical outcome in people living with HIV. Intensive research is warranted to identify any interactions of the co-existence of the two viruses in the immune system of HIV infected patients as common pathophysiology and molecular aspects are recognized. Human relations are diminished as a result of the social measures, and detailed recording of the consequences in this population is needed. Conclusion Further research could shed light on the common underlying molecular mechanisms of both conditions in an attempt to discover treatment regimens for SARS-CoV-2 infection.
目的
由 SARS-CoV-2 引起的 COVID-19 大流行正在全球范围内传播，影响着健康人群和患有潜在免疫缺陷的人群。人类免疫缺陷病毒 (HIV) 感染者是受这一全球危机影响最大的人群之一。
方法
旨在识别与 HIV 感染者中 COVID-19 大流行后果相关的文献进行文献检索。
结果
关于 HIV 感染者中 COVID-19 大流行的流行病学数据、HIV 和 SARS-CoV-2 之间的相互作用以及临床结局的文献数量正在迅速增加。需要进行深入研究，以确定两种病毒在 HIV 感染者免疫系统中共存时的任何相互作用，因为已经认识到它们具有共同的病理生理学和分子方面。由于社会措施，人际联系减少，因此需要详细记录该人群的后果。
结论
进一步的研究可以揭示这两种疾病共同的潜在分子机制，以期为 SARS-CoV-2 感染找到治疗方案。
