酒精戒断综合征患者的临床特征和健康结局：来自阿曼的一项观察性研究。
Clinical characteristics and health outcomes in patients with alcohol withdrawal syndrome: an observational study from Oman.
机构信息
From the Department of Pharmacy, Sultan Qaboos University Hospital, Muscat, Oman.
From the Internal Medicine Training Program, Oman Medical Specialty Board, Muscat, Oman.
出版信息
Ann Saudi Med. 2022 Jan-Feb;42(1):52-57. doi: 10.5144/0256-4947.2022.52. Epub 2022 Feb 3.
BACKGROUND
Globally, alcohol withdrawal syndrome (AWS) is considered a serious medical diagnosis associated with increasing morbidity and mortality. Little information has been reported on the scope of the problem in Oman.
OBJECTIVE
Study clinical characteristics, management, quality of care, and health outcomes of patients managed for AWS.
DESIGN
Retrospective medical record review.
SETTINGS
University hospital.
PATIENTS AND METHODS
The study included all patients with AWS admitted from 1 October 2019 to 30 September 2020. We collected demographic and clinical characteristics and did a univariate analysis of factors related to 90-day readmission.
MAIN OUTCOME MEASURES
Length of hospital stay, 90-day read-mission, referral rate to alcohol rehabilitation center.
SAMPLE SIZE AND CHARACTERISTICS
150 male patients with median (IQR) age of 39.5 (32-48) years.
RESULTS
Most patients (70.7%, n=106) were smokers and 44 (29.3%) had a history of drug abuse. The average length of hospital stay was 2.3 (0.9-4.6) days. Approximately 9% of total hospital bed days were used to care for patients with AWS. Chronic liver disease (35.3%), diabetes mellitus (24.7%), and hypertension (24.0%) were common among AWS patients. The 90-day readmission rate (32.7%) was high, and there was low referral to alcohol rehabilitation (16.7%). Diabetes and epilepsy were associated with 90-day readmission.
CONCLUSION
AWS is an important diagnosis that represents an important burden on acute medical services. Establishing a drug and alcohol service in our institution is an essential step to optimise care for patients with alcohol-related disorders.
LIMITATIONS
Retrospective, so unable to collect data on manifestations of AWS such as delirium tremens, which is the most severe form of AWS. Also, the reason for the lack of referral to an outpatient alcohol rehabilitation program was not apparent.
CONFLICT OF INTEREST
None.
背景
在全球范围内，酒精戒断综合征（AWS）被认为是一种严重的医疗诊断，与发病率和死亡率的增加有关。关于阿曼该问题的范围，鲜有报道。
目的
研究 AWS 患者的临床特征、管理、护理质量和健康结局。
设计
回顾性病历审查。
地点
大学医院。
患者和方法
本研究纳入了 2019 年 10 月 1 日至 2020 年 9 月 30 日期间因 AWS 住院的所有患者。我们收集了人口统计学和临床特征，并对与 90 天再入院相关的因素进行了单因素分析。
主要观察指标
住院时间、90 天再入院、转介至酒精康复中心的比例。
样本量和特征
共纳入 150 例男性患者，中位（IQR）年龄为 39.5（32-48）岁。
结果
大多数患者（70.7%，n=106）为吸烟者，44 例（29.3%）有药物滥用史。平均住院时间为 2.3（0.9-4.6）天。AWS 患者的总住院天数中，约有 9%用于治疗。AWS 患者中常见的合并症包括慢性肝病（35.3%）、糖尿病（24.7%）和高血压（24.0%）。90 天再入院率（32.7%）较高，而转介至酒精康复的比例较低（16.7%）。糖尿病和癫痫与 90 天再入院相关。
结论
AWS 是一个重要的诊断，对急性医疗服务构成了重要负担。在我们的机构建立药物和酒精服务是优化酒精相关疾病患者护理的重要步骤。
局限性
回顾性研究，因此无法收集 AWS 表现（如震颤性谵妄，这是 AWS 最严重的形式）的数据。此外，转介至门诊酒精康复计划的原因并不明显。
利益冲突
无。
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