慢性鼻-鼻窦炎伴鼻息肉患者的12年长期术后结局
Twelve-year long-term postoperative outcomes in patients with chronic rhinosinusitis with nasal polyps.
作者信息
Arancibia C, Langdon C, Mullol J, Alobid I
机构信息
Rhinology and Skull Base Unit, Department of Otorhinolaryngology, Hospital Clinic, Universitat de Barcelona, Spain.
Rhinology and Skull Base Unit, Department of Otorhinolaryngology, Hospital Clinic, Universitat de Barcelona, Spain; Institut dInvestigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.
出版信息
Rhinology. 2022 Apr 1;60(2):109-117. doi: 10.4193/Rhin21.148. Epub 2022 Mar 15.
BACKGROUND
Evidence regarding long-term postoperative follow-up of chronic rhinosinusitis with nasal polyps (CRSwNP) patients is scarce in the literature. The objective of the present study was to report long-term 12-year postoperative outcomes for CRSwNP patients.
METHODS
CRSwNP patients were prospectively followed after endoscopic sinus surgery. Sinonasal symptoms, nasal polyp score (NPS), Barcelona Smell Test 24 (BAST-24), Lund-Mackay Score (LMS), and Medical Outcome Study Short Form-36 (SF-36) questionnaire were assessed before and 12 years after surgery.
RESULTS
At long-term follow-up (median, 12 years), a strong improvement was noted for all patients (N=76) in nasal symptoms score, NPS, BAST-24, and LMS scores compared with baseline. No long-term improvement in SF-36 was found.
CONCLUSION
Patients with CRSwNP have a long-term 12-year postoperative improvement in nasal symptoms, polyp size, computed tomography, and olfaction.
背景
关于鼻息肉慢性鼻窦炎（CRSwNP）患者术后长期随访的证据在文献中很少见。本研究的目的是报告CRSwNP患者术后12年的长期结局。
方法
对CRSwNP患者在内镜鼻窦手术后进行前瞻性随访。在手术前和手术后12年评估鼻窦症状、鼻息肉评分（NPS）、巴塞罗那嗅觉测试24（BAST-24）、伦德-麦凯评分（LMS）和医学结局研究简表36（SF-36）问卷。
结果
在长期随访（中位数为12年）时，与基线相比，所有患者（N = 76）的鼻症状评分、NPS、BAST-24和LMS评分均有显著改善。未发现SF-36有长期改善。
结论
CRSwNP患者在术后12年的长期随访中，鼻症状、息肉大小、计算机断层扫描和嗅觉方面均有改善。
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