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与胰岛素治疗导致的组织并发症相关的因素:一项横断面研究。

Factors related to tissue complications resulting from insulin therapy: a cross-sectional study.

机构信息

Universidade Federal da Paraíba, Programa de Pós-graduação em Enfermagem, João Pessoa, PB, Brazil.

Hospital Municipal Santa Isabel, João Pessoa, PB, Brazil.

出版信息

Rev Esc Enferm USP. 2022 Jan 28;56:e20210249. doi: 10.1590/1980-220X-REEUSP-2021-0249. eCollection 2022.

DOI:10.1590/1980-220X-REEUSP-2021-0249
PMID:35112702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10145229/
Abstract

OBJECTIVE

To identify factors related to tissue complications resulting from insulin therapy.

METHOD

This is a descriptive, cross-sectional study carried out in a capital of northeastern Brazil. A semi-structured form and an observation guide were applied to assess the performance of insulin preparation and administration techniques. Descriptive statistics, association test, and multivariate logistic regression were used for data analysis.

RESULTS

Most participants were female (74.2%), aged between 51 and 70 years (50.0%), and had nine to eleven years of education (36.7%). The presence of some type of local complication in 73.5% of the participants and the failure to rotate the injection sites in 82.3% are highlighted. Being single/widowed and not rotating insulin application sites were related to local complications and increased the chances of their occurrence by 3.51 and 6.70 times, respectively.

CONCLUSION

Marital status and nonrotation of injection site were related to the increased chances of tissue complications resulting from insulin therapy.

摘要

目的

确定与胰岛素治疗导致的组织并发症相关的因素。

方法

这是在巴西东北部一省会城市进行的描述性、横断面研究。采用半结构式表格和观察指南评估胰岛素准备和给药技术的执行情况。采用描述性统计、关联检验和多变量逻辑回归进行数据分析。

结果

大多数参与者为女性(74.2%),年龄在 51 至 70 岁之间(50.0%),受教育程度为九年至十一年(36.7%)。73.5%的参与者存在某种类型的局部并发症,82.3%的参与者未能轮换注射部位。单身/丧偶以及不轮换胰岛素注射部位与局部并发症有关,发生局部并发症的几率分别增加 3.51 倍和 6.70 倍。

结论

婚姻状况和注射部位不轮换与胰岛素治疗导致的组织并发症发生几率增加有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d3c/10145229/bc2792283c74/1980-220X-reeusp-56-e20210249-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d3c/10145229/bc2792283c74/1980-220X-reeusp-56-e20210249-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d3c/10145229/bc2792283c74/1980-220X-reeusp-56-e20210249-gf01.jpg

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本文引用的文献

1
Insulin therapy practice performed by people with diabetes in Primary Healthcare.
Rev Esc Enferm USP. 2020 Oct 12;54:e03620. doi: 10.1590/S1980-220X2019002903620. eCollection 2020.
2
Insulin Injection Technique is Associated with Glycemic Variability in Patients with Type 2 Diabetes.胰岛素注射技术与2型糖尿病患者的血糖变异性相关。
Diabetes Ther. 2018 Dec;9(6):2347-2356. doi: 10.1007/s13300-018-0522-1. Epub 2018 Oct 19.
3
New Insulin Delivery Recommendations.新胰岛素输送推荐意见。
Mayo Clin Proc. 2016 Sep;91(9):1231-55. doi: 10.1016/j.mayocp.2016.06.010.
4
Lipodystrophy in Insulin-Treated Subjects and Other Injection-Site Skin Reactions: Are We Sure Everything is Clear?胰岛素治疗患者的脂肪营养不良及其他注射部位皮肤反应:我们确定一切都清楚了吗?
Diabetes Ther. 2016 Sep;7(3):401-9. doi: 10.1007/s13300-016-0187-6. Epub 2016 Jul 25.