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超短效胰岛素类似物——预防 1 型糖尿病患者餐后高血糖和改善生活质量的新方法——病例报告。

Ultrafast acting insulin analog - a new way to prevent postprandial hyperglycemia and improve quality of life in type 1 diabetes patients - case reports.

机构信息

Department of Pediatrics, Oncology, Haematology and Diabetology, Medical University of Lodz, Poland.

出版信息

Pediatr Endocrinol Diabetes Metab. 2021;27(4):305-310. doi: 10.5114/pedm.2022.112621.

DOI:10.5114/pedm.2022.112621
PMID:35114772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10226363/
Abstract

The aim of modern insulin therapy used in the treatment of type 1 diabetes mellitus is to mimic the physiological secretion of insulin in order to ensure stable normoglycemia while maintaining the greatest possible comfort of life for diabetic patients. New ultra-fast insulin analogs that can be administered immediately before a meal contribute to the improvement of postprandial glycemia and the quality of life of patients. We presented two cases illustrating the effectiveness and safety of the use of an ultra-fast-acting insulin analog in the treatment of postprandial hyperglycemia in children with type 1 diabetes.

摘要

目的在于使用现代胰岛素治疗来模拟 1 型糖尿病患者生理胰岛素分泌,以确保稳定的正常血糖,同时保持糖尿病患者最大可能的生活舒适度。新型速效胰岛素类似物可以在餐前即刻给药,有助于改善餐后血糖和患者生活质量。我们报告了两例病例,说明了速效胰岛素类似物在治疗 1 型糖尿病儿童餐后高血糖中的有效性和安全性。

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本文引用的文献

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Clin Diabetes. 2021 Oct;39(4):347-357. doi: 10.2337/cd20-0117.
2
Comparable Glucose Control with Fast-Acting Insulin Aspart Versus Insulin Aspart Using a Second-Generation Hybrid Closed-Loop System During Exercise.在运动期间使用第二代混合闭环系统时,门冬胰岛素快速起效制剂与门冬胰岛素实现可比的血糖控制。
Diabetes Technol Ther. 2022 Feb;24(2):93-101. doi: 10.1089/dia.2021.0221. Epub 2021 Oct 8.
3
Fast-Acting Insulin Aspart Versus Insulin Aspart Using a Second-Generation Hybrid Closed-Loop System in Adults With Type 1 Diabetes: A Randomized, Open-Label, Crossover Trial.
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Diabetes Care. 2021 Aug 6. doi: 10.2337/dc21-0814.
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Fast Acting Insulin Aspart Compared with Insulin Aspart in the Medtronic 670G Hybrid Closed Loop System in Type 1 Diabetes: An Open Label Crossover Study.门冬胰岛素类似物与赖脯胰岛素类似物在 1 型糖尿病美敦力 670G 混合闭环系统中的比较:一项开放标签交叉研究。
Diabetes Technol Ther. 2021 Apr;23(4):286-292. doi: 10.1089/dia.2020.0500. Epub 2021 Mar 8.
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Diabetes Technol Ther. 2021 Mar;23(3):203-212. doi: 10.1089/dia.2020.0360. Epub 2020 Oct 21.
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