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临床指南:管理耐多药结核病治疗相关听力损失的并发症,在尼日利亚卡诺评估实施准确性

Clinical guidelines for managing hearing loss as a complication of drug-resistant tuberculosis treatment: an evaluation of implementation fidelity in Kano, Nigeria.

机构信息

Division of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Department of Otorhinolaryngology-Head and Neck Surgery, Aminu Kano Teaching Hospital, No. 2 Hospital Road, off Zaria Road, PMB, Kano, 3452, Nigeria.

出版信息

BMC Health Serv Res. 2022 Feb 3;22(1):142. doi: 10.1186/s12913-022-07536-y.

DOI:10.1186/s12913-022-07536-y
PMID:35115002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8812187/
Abstract

BACKGROUND

Nigeria has a high burden of Tuberculosis (TB) including Drug-resistant Tuberculosis (DR-TB) and hearing loss. Despite several efforts directed toward its control, many patients fail to respond to treatment, having developed DR-TB. Lack of adherence to the DR-TB guidelines/improper implementation of the guideline has been identified as one of the factors impeding on effective treatment. This study sought to measure the implementation fidelity of health workers to management guidelines for hearing loss resulting from DR-TB treatment and to identify its determinants.

METHOD

A questionnaire-based cross-sectional study was conducted at the Infectious Disease Hospital, Kano. Implementation fidelity of the Programmatic Management guidelines for the treatment of Drug-resistant Tuberculosis was measured under the four domains of content, coverage, duration and frequency. The determinants examined are intervention complexity, facilitation strategies, quality of delivery and participant responsiveness as proposed by the Carroll et al. framework. Other determinants used are age, sex, professional cadre and work experience of healthcare providers.

RESULTS

The Implementation fidelity score ranged from 40 to 64% with a mean of 47.6%. Quality of delivery, intervention complexity, participants' responsiveness, and being a medical doctor exerted a positive effect on implementation fidelity while facilitation strategy, age and work experience exerted a negative effect on implementation fidelity.

CONCLUSION

The implementation fidelity of management guidelines for hearing loss resulting from DR-TB treatment was low. Implementation fidelity should be assessed early and at intervals in the course of implementing the Programmatic Management of Drug-resistant Tuberculosis guideline and indeed, in the implementation of any intervention.

摘要

背景

尼日利亚结核病(TB)负担沉重,包括耐药结核病(DR-TB)和听力损失。尽管为控制结核病做出了多项努力,但许多患者因发展为 DR-TB 而未能对治疗产生反应。缺乏对 DR-TB 指南的遵守或对指南的不当执行已被确定为阻碍有效治疗的因素之一。本研究旨在衡量卫生工作者对 DR-TB 治疗引起的听力损失管理指南的实施情况,并确定其决定因素。

方法

在卡诺传染病医院进行了一项基于问卷的横断面研究。根据 Carroll 等人提出的框架,在内容、覆盖范围、持续时间和频率四个领域测量了《耐多药结核病治疗规划管理指南》的实施情况。检查的决定因素是干预的复杂性、促进策略、交付质量和参与者的响应性。使用的其他决定因素是医疗保健提供者的年龄、性别、专业职务和工作经验。

结果

实施一致性评分范围为 40%至 64%,平均为 47.6%。交付质量、干预复杂性、参与者的响应能力和作为一名医生对实施一致性产生积极影响,而促进策略、年龄和工作经验对实施一致性产生负面影响。

结论

DR-TB 治疗引起的听力损失管理指南的实施一致性较低。在实施耐药结核病规划管理指南以及实施任何干预措施的过程中,应尽早并在间隔时间评估实施一致性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/182f/8812187/823c38acc70a/12913_2022_7536_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/182f/8812187/823c38acc70a/12913_2022_7536_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/182f/8812187/823c38acc70a/12913_2022_7536_Fig1_HTML.jpg

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本文引用的文献

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2
Evaluating fidelity of community health worker roles in malaria prevention and control programs in Livingstone District, Zambia-A bottleneck analysis.评估赞比亚利文斯通地区疟疾预防和控制项目中社区卫生工作者角色的保真度——瓶颈分析。
BMC Health Serv Res. 2020 Jul 2;20(1):612. doi: 10.1186/s12913-020-05458-1.
3
Second-line injectable induced ototoxicity in drug resistant tuberculosis: A systematic review of Indian studies.
耐多药结核病二线注射剂所致耳毒性:印度研究的系统评价
Indian J Tuberc. 2019 Apr;66(2):279-287. doi: 10.1016/j.ijtb.2019.04.007. Epub 2019 Apr 11.
4
Effectiveness of the Diagnose-Intervene- Verify-Adjust (DIVA) model for integrated primary healthcare planning and performance improvement: an embedded mixed methods evaluation in Kaduna state, Nigeria.诊断-干预-验证-调整(DIVA)模型在综合初级卫生保健规划和绩效改进中的有效性:尼日利亚卡杜纳州的一项嵌入式混合方法评估。
BMJ Open. 2019 Mar 30;9(3):e026016. doi: 10.1136/bmjopen-2018-026016.
5
The challenges of training, support and assessment of healthcare support workers: A qualitative study of experiences in three English acute hospitals.培训、支持和评估医疗支持人员的挑战:对英国三家急症医院的经验进行的定性研究。
Int J Nurs Stud. 2018 Mar;79:145-153. doi: 10.1016/j.ijnurstu.2017.11.010. Epub 2017 Nov 29.
6
Prevalence of drug-resistant tuberculosis in Nigeria: A systematic review and meta-analysis.尼日利亚耐多药结核病的患病率:一项系统评价与荟萃分析。
PLoS One. 2017 Jul 13;12(7):e0180996. doi: 10.1371/journal.pone.0180996. eCollection 2017.
7
Study of streptomycin-induced ototoxicity: protocol for a longitudinal study.链霉素诱导耳毒性的研究:一项纵向研究方案。
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8
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9
Audiological monitoring for ototoxic tuberculosis, human immunodeficiency virus and cancer therapies in a developing world setting.在发展中世界环境下对耳毒性结核病、人类免疫缺陷病毒和癌症治疗进行听力学监测。
J Laryngol Otol. 2012 Jun;126(6):548-51. doi: 10.1017/S0022215112000357. Epub 2012 Mar 30.
10
Outcomes for implementation research: conceptual distinctions, measurement challenges, and research agenda.实施研究的结果:概念区别、测量挑战和研究议程。
Adm Policy Ment Health. 2011 Mar;38(2):65-76. doi: 10.1007/s10488-010-0319-7.