新型工具应对新型真菌——耳念珠菌。
New tools for the new bug Candida auris.
机构信息
Institute of Medical Sciences (IMS), University of Aberdeen, Aberdeen, UK.
Univ Angers, Univ Brest, IRF, SFR ICAT, F-49000 Angers, France.
出版信息
Trends Microbiol. 2022 Mar;30(3):203-205. doi: 10.1016/j.tim.2022.01.010. Epub 2022 Feb 1.
PMID:35115186
Abstract
Candida auris is a recently emerged yeast pathogen of humans causing severe hospital-acquired systemic infections. It is of the utmost importance to understand the genetic and cellular basis of its virulence and pathogenicity. In a recent study, Santana and O'Meara generated forward and reverse genetic tools to manipulate C. auris.
摘要
耳念珠菌是一种新近出现的人类酵母病原体，可导致严重的医院获得性全身感染。了解其毒力和致病性的遗传和细胞基础至关重要。在最近的一项研究中，Santana 和 O'Meara 生成了正向和反向遗传工具来操纵耳念珠菌。
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