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取卵后,我们能否预测第 5 天胚胎移植或冷冻的机会?

After egg collection, can we predict the chance of embryos for day 5 transfer or freezing?

机构信息

Human Development and Health, University of Southampton, Southampton, UK.

IT Innovation Centre, School of Electronics and Computer Science, University of Southampton, Southampton, UK.

出版信息

Reprod Fertil. 2021 Sep 9;2(3):L1-L3. doi: 10.1530/RAF-21-0018. eCollection 2021 Jul.

DOI:10.1530/RAF-21-0018
PMID:35118396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8801027/
Abstract

Even partway through an IVF cycle, at the point when a woman's eggs have been collected, it is hard to provide reliable answers to the common question of 'Am I likely to have a good embryo to transfer?' Sometimes, it only takes one good egg to be successful. However, doctors and patients are acutely aware that low egg numbers, older age and having conditions such as endometriosis can stack the odds against success. We have developed a model to try and answer this question for those patients who wish for more information to help guide their expectations after egg collection. A new tool is presented to predict whether a woman having IVF treatment will have a good enough embryo either to transfer on day 5 or freeze. It was built using information from all 2015 to 2016 UK cycles and predicts using age, number of eggs collected and cause of subfertility.

摘要

即使在试管婴儿周期进行到一半,也就是女性取卵的时候,也很难对常见的问题“我有可能有一个好的胚胎移植吗?”给出可靠的答案。有时候,只需要一个好的卵子就能成功。然而,医生和患者都清楚地知道,卵子数量少、年龄大以及患有子宫内膜异位症等疾病会使成功的几率降低。我们已经开发了一种模型,试图为那些希望获得更多信息来帮助指导取卵后预期的患者回答这个问题。我们提出了一种新的工具,用于预测接受试管婴儿治疗的女性是否有足够好的胚胎在第 5 天进行移植或冷冻。该模型使用了 2015 年至 2016 年所有英国周期的数据,并根据年龄、采集的卵子数量和不孕原因进行预测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6e7/8801027/f7a9aa95613c/RAF-21-0018fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6e7/8801027/f7a9aa95613c/RAF-21-0018fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6e7/8801027/f7a9aa95613c/RAF-21-0018fig1.jpg

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After egg collection, can we predict the chance of embryos for day 5 transfer or freezing?取卵后,我们能否预测第 5 天胚胎移植或冷冻的机会?
Reprod Fertil. 2021 Sep 9;2(3):L1-L3. doi: 10.1530/RAF-21-0018. eCollection 2021 Jul.
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