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罕见的外周复合型牙瘤病例报告及文献复习。

A Rare Case of Peripheral Compound Odontoma and Review of the Literature.

机构信息

Department of Tumour Pathology, Institute of Oncology, Istanbul University, Fatih, 34093, Istanbul, Turkey.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.

出版信息

Head Neck Pathol. 2022 Sep;16(3):913-917. doi: 10.1007/s12105-022-01421-0. Epub 2022 Feb 4.

DOI:10.1007/s12105-022-01421-0
PMID:35119618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9424475/
Abstract

Peripheral or extraosseous odontogenic tumors are rare oral soft tissue enlargements which demonstrate the same histologic features of their intraosseous counterparts but emerge in gingiva and mucosa. In this paper we report a case of peripheral odontoma in a 12-years-old female patient presented asymptomatic swelling in the palatal site. After the clinical and radiographic examination, excisional biopsy was applied to the lesion located entirely in the soft tissue of maxillary incisors. Histopathologically presence of tooth-like structures containing dentin with regular canals and partly enamel matrix were observed. Our aim is to present the extremely rare case of peripheral odontoma and to review the literature for demonstrating the frequency and clinicopathologic features of this entity.

摘要

外周或骨外牙源性肿瘤是罕见的口腔软组织增大,其表现出与骨内肿瘤相同的组织学特征,但出现在牙龈和黏膜中。本文报告了一例 12 岁女性患者的外周牙瘤病例,该患者无症状性腭部肿胀。经过临床和影像学检查,对位于上颌切牙完全位于软组织内的病变进行了切除活检。组织病理学观察到存在牙齿样结构,包含有规则管腔的牙本质和部分釉基质。我们的目的是报告外周牙瘤这一极其罕见的病例,并通过文献复习来阐述该实体的发病率和临床病理特征。

相似文献

1
A Rare Case of Peripheral Compound Odontoma and Review of the Literature.罕见的外周复合型牙瘤病例报告及文献复习。
Head Neck Pathol. 2022 Sep;16(3):913-917. doi: 10.1007/s12105-022-01421-0. Epub 2022 Feb 4.
2
Peripheral compound odontoma: A rare case report and literature review.
J Cutan Pathol. 2020 Aug;47(8):720-724. doi: 10.1111/cup.13676. Epub 2020 Mar 31.
3
Peripheral compound odontoma erupting in the gingiva.牙龈内萌出的外周性复合性牙瘤。
Head Face Med. 2013 Jun 11;9:15. doi: 10.1186/1746-160X-9-15.
4
Peripheral ameloblastic fibro-odontoma-Report of 2 cases of a very rare entity.外周型成釉细胞纤维牙瘤——2例极为罕见病例的报告
Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 Jun;133(6):e178-e182. doi: 10.1016/j.oooo.2021.09.006. Epub 2021 Sep 20.
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Peripheral ameloblastic fibroma of the maxilla: report of a case and review of the literature.上颌骨外周性成釉细胞纤维瘤:1例报告并文献复习
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 May;105(5):e46-8. doi: 10.1016/j.tripleo.2008.01.012. Epub 2008 Mar 4.
6
Ameloblastic fibro-odontoma masquerading as odontoma.伪装成牙瘤的成釉细胞纤维牙瘤
Indian J Dent Res. 2011 Jul-Aug;22(4):616. doi: 10.4103/0970-9290.90332.
7
[A case of a calcifying odontogenic cyst associated with odontoma inducing impaction of a deciduous tooth].[一例与牙瘤相关的钙化牙源性囊肿导致乳牙阻生]
Shoni Shikagaku Zasshi. 1991;29(1):181-5.
8
A rare case report of an adenomatoid odontogenic tumor associated with odontoma in the maxilla.上颌骨中与牙瘤相关的腺样牙源性肿瘤的罕见病例报告。
Int J Surg Case Rep. 2017;39:245-249. doi: 10.1016/j.ijscr.2017.08.020. Epub 2017 Aug 24.
9
Adenomatoid odontogenic tumor developing in association with an odontoma: report of a case.与牙瘤相关的腺样牙源性肿瘤:一例报告。
Quintessence Int. 2008 Sep;39(8):693-7.
10
[The ameloblastic fibro-odontoma].[成釉细胞纤维牙瘤]
Dtsch Zahnarztl Z. 1991 Jan;46(1):71-3.

本文引用的文献

1
Peripheral developing odontoma: Is it so rare?外周发育性牙瘤:真的如此罕见吗?
J Cutan Pathol. 2021 Jan;48(1):200-201. doi: 10.1111/cup.13862. Epub 2020 Sep 10.
2
Peripheral compound odontoma: A rare case report and literature review.
J Cutan Pathol. 2020 Aug;47(8):720-724. doi: 10.1111/cup.13676. Epub 2020 Mar 31.
3
Odontogenic Tumors.牙源性肿瘤
Dent Clin North Am. 2020 Jan;64(1):121-138. doi: 10.1016/j.cden.2019.08.008. Epub 2019 Oct 18.
4
The Importance of Histopathological Examination to the Final Diagnosis of Peripheral Odontogenic Tumors: A Case Report of a Peripheral Odontoma.组织病理学检查对周围性牙源性肿瘤最终诊断的重要性:1例外周性牙瘤病例报告
Case Rep Dent. 2019 Sep 8;2019:9712816. doi: 10.1155/2019/9712816. eCollection 2019.
5
Wnt/β-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development.Wnt/β-catenin 信号通路在牙瘤中被激活,降低 Sema3A 的表达,从而调节牙源性上皮细胞的增殖和牙胚发育。
Sci Rep. 2019 Mar 12;9(1):4257. doi: 10.1038/s41598-019-39686-1.
6
Odontogenic Cysts and Tumors.牙源性囊肿和肿瘤
Ann Plast Surg. 2019 Apr;82(4):469-477. doi: 10.1097/SAP.0000000000001738.
7
Gingival complex odontoma: a rare case report with a review of the literature.牙龈复合性牙瘤:一例罕见病例报告并文献复习
Autops Case Rep. 2018 Feb 27;8(1):e2018009. doi: 10.4322/acr.2018.009. eCollection 2018 Jan-Mar.
8
Odontogenic tumors: where are we in 2017 ?牙源性肿瘤:2017年我们处于什么阶段?
J Istanb Univ Fac Dent. 2017 Dec 2;51(3 Suppl 1):S10-S30. doi: 10.17096/jiufd.52886. eCollection 2017.
9
The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2017 (4th) Edition.世界卫生组织牙源性病变分类:2017年(第4版)变化总结
Turk Patoloji Derg. 2018;34(1). doi: 10.5146/tjpath.2017.01410.
10
Peripheral Developing Odontoma or Peripheral Ameloblastic Fibroodontoma: A Rare Challenging Case.外周发育性牙瘤或外周成釉细胞纤维牙瘤:一例罕见的疑难病例。
Case Rep Dent. 2016;2016:9379017. doi: 10.1155/2016/9379017. Epub 2016 Feb 15.