Department of Coatings and Polymeric Materials, North Dakota State University, Fargo North Dakota 58108, United States.
Langmuir. 2022 Feb 15;38(6):2066-2075. doi: 10.1021/acs.langmuir.1c03033. Epub 2022 Feb 4.
We studied self-assembly and colloidal properties of poly(ethylene glycol) (pEG) conjugated sucrose soyate polyols (PSSP). These molecular platforms were synthesized by covalently connecting PEGs of different molecular weights () (12 and 16 ethylene oxide units) to epoxidized sucrose soyate (ESS). The synthesized PSSP products showed amphiphilicity, reduced water surface tension, and exhibited critical Aggregation Concentration (CAC) within the range of 0.3-0.4 mg/mL. We observed that PSSP self-assembles in water in the form of nanoparticles without the need of any cosolvents. These nanoparticles exhibited number-average hydrodynamic diameter of 120 ± 8 nm with a polydispersity index (PDI) of <0.3, and negatively charged surfaces. We also found out that PSSP nanoparticles can encapsulate and homogeneously distribute a hydrophobic model compound, such as a phthalocyanine dye, Solvent Blue-70 (BL-70), on a metal surface. Collectively, our studies explored and demonstrated the possibility of molecular diversification of biobased starting materials to form amphiphilic nanoparticles with industrially relevant colloidal and surface properties.
我们研究了聚乙二醇（pEG）接枝蔗糖大豆醇（PSSP）的自组装和胶体性质。这些分子平台是通过共价连接不同分子量的 PEG（12 和 16 个环氧乙烷单元）到环氧化蔗糖大豆醇（ESS）来合成的。合成的 PSSP 产物表现出两亲性，降低了水的表面张力，并在 0.3-0.4mg/mL 的范围内表现出临界聚集浓度（CAC）。我们观察到 PSSP 在水中自组装成纳米粒子，而无需任何共溶剂。这些纳米粒子表现出 120±8nm 的数均水动力直径和 <0.3 的多分散指数（PDI），以及带负电荷的表面。我们还发现 PSSP 纳米粒子可以在金属表面上包封和均匀分布疏水性模型化合物，如酞菁染料溶剂蓝 70（BL-70）。总的来说，我们的研究探索并证明了生物基起始材料的分子多样化的可能性，以形成具有工业相关胶体和表面性质的两亲性纳米粒子。
