Zarzour M, Bou Khalil R
Saint-Joseph University, rue de Damas B.P. 17-5208, 1104 2020 Liban, Lebanon.
Saint-Joseph University, rue de Damas B.P. 17-5208, 1104 2020 Liban, Lebanon.
Encephale. 2022 Dec;48(6):725-728. doi: 10.1016/j.encep.2021.09.005. Epub 2022 Feb 1.
Fibromyalgia is a chronic syndrome characterized by widespread muscular pain and tenderness with no evidence of soft tissue inflammation. Early-life stressors and traumatic events have been described to increase the risk of developing a number of psychiatric conditions, and conditions related to chronic pain in later life such as fibromyalgia on the other hand. In this overview of the literature on the topic, we present the impact that traumatic life events can have on fibromyalgia symptoms through serotonin activity on pain perception and personality traits.
纤维肌痛是一种慢性综合征,其特征为广泛的肌肉疼痛和压痛,且无软组织炎症迹象。已有研究表明,早年生活中的压力源和创伤性事件会增加患多种精神疾病的风险,而另一方面,也会增加晚年患慢性疼痛相关疾病(如纤维肌痛)的风险。在本次关于该主题的文献综述中,我们阐述了创伤性生活事件通过血清素对疼痛感知和人格特质的影响,进而对纤维肌痛症状产生的作用。