Department of Stomatology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Department of Stomatology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Int J Oral Maxillofac Surg. 2022 Oct;51(10):1273-1278. doi: 10.1016/j.ijom.2022.01.015. Epub 2022 Feb 1.
Central mucoepidermoid carcinoma (MEC) of the jaw is a rare malignant neoplasm, even rarer in teenagers. Radical surgical resection, such as en bloc resection or segmental resection, is the main treatment for MEC of the jaw. This surgical treatment results in a loss of integrity of the jaw. The successful application of iodine-125 brachytherapy for the treatment of intraosseous MEC of the mandible in an 11-year-old girl is reported here. No local recurrence or distant metastasis was observed during 6 years of follow-up. The integrity of the mandible was preserved and the development of the mandible was not significantly affected. Iodine-125 brachytherapy is a potential alternative treatment for central mucoepidermoid carcinoma of the jaw, especially in teenagers, and may preserve the continuity and function of the jaw.
颌骨中心黏液表皮样癌（MEC）是一种罕见的恶性肿瘤，在青少年中更为罕见。颌骨 MEC 的主要治疗方法是根治性手术切除，如整块切除或节段性切除。这种手术治疗会导致颌骨完整性丧失。本文报告了一例 11 岁女孩颌骨内骨 MEC 成功应用碘 125 近距离放疗的情况。6 年随访期内未见局部复发或远处转移。颌骨的完整性得以保留，颌骨的发育也没有受到明显影响。碘 125 近距离放疗是治疗颌骨中心黏液表皮样癌的一种潜在替代方法，特别是在青少年中，可能保留颌骨的连续性和功能。
