Department of Neurology, Island Hospital, Penang, Malaysia.
Department of Neurology, LohGuanLye Specialists Centre, Penang, Malaysia.
Parkinsonism Relat Disord. 2022 Feb;95:138-142. doi: 10.1016/j.parkreldis.2022.01.013. Epub 2022 Jan 26.
Latah is a culture-specific syndrome characterized by exaggerated startle response, echolalia, palilalia, echopraxia, coprolalia, forced obedience and involuntary vocalization in response to startle. Latah is stimulus-induced and is associated with behavior and psychiatric features. The aim of this review is to provide a comprehensive description on latah from a regional perspective based on previous literature and clinical experiences and highlight the clinical characteristics of latah from a movement disorders perspective. The pathophysiology of latah is complex and poorly understood although psychological stressors have been implicated. In view of the distressing psychosocial impact of latah, this neuropsychiatric startle syndrome warrants further studies to understand the pathophysiology and identify the appropriate treatments.
拉萨尔症候群是一种文化特异性综合征，其特征为受到惊吓时出现夸张的惊跳反应、模仿言语、重复言语、模仿动作、秽语、强迫服从和不由自主的发声。拉萨尔症候群是由刺激引起的，与行为和精神特征有关。本综述的目的是基于以往的文献和临床经验，从区域性角度对拉萨尔症候群进行全面描述，并从运动障碍的角度突出拉萨尔症候群的临床特征。尽管心理压力与拉萨尔症候群有关，但拉萨尔症候群的发病机制复杂且尚未完全了解。鉴于拉萨尔症候群对社会心理的困扰，这种神经精神性惊跳综合征需要进一步研究以了解其发病机制并确定适当的治疗方法。
