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临床更新:COVID-19 对急诊医生的影响:表现与评估。

Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation.

机构信息

SAUSHEC, Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, USA.

121 Field Hospital, Camp Humphreys, US Army, Republic of Korea.

出版信息

Am J Emerg Med. 2022 Apr;54:46-57. doi: 10.1016/j.ajem.2022.01.028. Epub 2022 Jan 21.

Abstract

INTRODUCTION

Coronavirus disease of 2019 (COVID-19) has resulted in millions of cases worldwide. As the pandemic has progressed, the understanding of this disease has evolved.

OBJECTIVE

This first in a two-part series on COVID-19 updates provides a focused overview of the presentation and evaluation of COVID-19 for emergency clinicians.

DISCUSSION

COVID-19, caused by Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), has resulted in significant morbidity and mortality worldwide. Several variants exist, including a variant of concern known as Delta (B.1.617.2 lineage) and the Omicron variant (B.1.1.529 lineage). The Delta variant is associated with higher infectivity and poor patient outcomes, and the Omicron variant has resulted in a significant increase in infections. While over 80% of patients experience mild symptoms, a significant proportion can be critically ill, including those who are older and those with comorbidities. Upper respiratory symptoms, fever, and changes in taste/smell remain the most common presenting symptoms. Extrapulmonary complications are numerous and may be severe, including the cardiovascular, neurologic, gastrointestinal, and dermatologic systems. Emergency department evaluation includes focused testing for COVID-19 and assessment of end-organ injury. Imaging may include chest radiography, computed tomography, or ultrasound. Several risk scores may assist in prognostication, including the 4C (Coronavirus Clinical Characterisation Consortium) score, quick COVID Severity Index (qCSI), NEWS2, and the PRIEST score, but these should only supplement and not replace clinical judgment.

CONCLUSION

This review provides a focused update of the presentation and evaluation of COVID-19 for emergency clinicians.

摘要

简介

2019 年冠状病毒病(COVID-19)已在全球范围内导致数百万人患病。随着大流行的发展,人们对这种疾病的认识也在不断发展。

目的

本系列 COVID-19 更新的第一部分重点介绍了 COVID-19 对急诊临床医生的表现和评估。

讨论

由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的 COVID-19 在全球范围内导致了大量的发病率和死亡率。存在几种变体,包括一种称为 Delta(B.1.617.2 谱系)的关注变体和 Omicron 变体(B.1.1.529 谱系)。Delta 变体与更高的传染性和较差的患者预后相关,而 Omicron 变体导致感染显著增加。虽然超过 80%的患者出现轻度症状,但相当一部分患者病情严重,包括年龄较大和合并症的患者。上呼吸道症状、发热和味觉/嗅觉改变仍然是最常见的症状。肺外并发症很多,可能很严重,包括心血管、神经、胃肠道和皮肤系统。急诊科评估包括对 COVID-19 的有针对性检测和对终末器官损伤的评估。影像学检查可能包括胸部 X 光、计算机断层扫描或超声。几种风险评分可用于预后评估,包括 4C(冠状病毒临床特征联盟)评分、快速 COVID 严重指数(qCSI)、NEWS2 和 PRIEST 评分,但这些评分只能补充而不能替代临床判断。

结论

本综述为急诊临床医生提供了 COVID-19 表现和评估的重点更新。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23b2/8779861/52b5d52e6ed1/gr1a_lrg.jpg

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