Sologub L I, Pashkovskaia I S, Gurskaia N I, Sen'kus' Ia T
Eksp Onkol. 1986;8(1):13-6.
The data concerning proteolytic enzymes in human and animal malignant tumours are reviewed. The activity of these proteinases, its changes in the course of the disease, intracellular localization and secretion into the extracellular space and blood are discussed. The role of proteolytic enzymes including the role of plasminogen activator in tumour progress and during the metastasis development is considered.
本文综述了有关人类和动物恶性肿瘤中蛋白水解酶的数据。讨论了这些蛋白酶的活性、其在疾病过程中的变化、细胞内定位以及向细胞外空间和血液中的分泌情况。还探讨了蛋白水解酶的作用,包括纤溶酶原激活剂在肿瘤进展和转移发展过程中的作用。