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实施 COVID-19 胸部放射治疗计划的初步方法。

Preliminary Approach to Implementing a COVID-19 Thoracic Radiation Therapy Program.

机构信息

Department of Radiation Oncology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois.

Department of Radiation Medicine, Lowell General Hospital, Lowell, Massachusetts.

出版信息

Pract Radiat Oncol. 2022 Jul-Aug;12(4):363-366. doi: 10.1016/j.prro.2021.12.014. Epub 2022 Feb 2.

DOI:10.1016/j.prro.2021.12.014
PMID:35123063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8808431/
Abstract

The value of low-dose whole thoracic radiation therapy (LD-WTRT) for SARS-CoV-2 (COVID-19) pneumonia is unknown. Should ongoing clinical trials demonstrate that LD-WTRT proves effective for COVID-19 pneumonia recovery, widespread rapid implementation will be helpful globally. Our aim was to outline a pragmatic process for safe and efficient administration of LD-WTRT to patients with COVID-19 pneumonia that could be implemented successfully in a community hospital setting based on participation in the PreVent clinical trial of LD-WTRT.

摘要

低剂量全胸放射治疗（LD-WTRT）治疗 SARS-CoV-2（COVID-19）肺炎的价值尚不清楚。如果正在进行的临床试验证明 LD-WTRT 对 COVID-19 肺炎的恢复有效，那么在全球范围内广泛快速实施将是有帮助的。我们的目的是根据参与 LD-WTRT 的 PreVent 临床试验，为 COVID-19 肺炎患者安全有效地实施 LD-WTRT 制定一个实用的流程，该流程可以在社区医院环境中成功实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6914/8808431/077c00ed7769/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6914/8808431/077c00ed7769/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6914/8808431/077c00ed7769/gr1_lrg.jpg

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本文引用的文献

1
COVID-19 and low-dose radiation therapy.新型冠状病毒肺炎与低剂量放射治疗
Radiat Med Prot. 2021 Dec;2(4):139-145. doi: 10.1016/j.radmp.2021.09.004. Epub 2021 Sep 10.
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Low-dose whole-lung irradiation in severe COVID-19 pneumonia: a controlled clinical trial.低剂量全肺照射治疗重症 COVID-19 肺炎：一项对照临床试验。
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Low-dose radiation therapy (LDRT) for COVID-19 and its deadlier variants.低剂量辐射疗法（LDRT）治疗 COVID-19 及其更致命的变体。
Arch Toxicol. 2021 Oct;95(10):3425-3432. doi: 10.1007/s00204-021-03124-x. Epub 2021 Jul 24.
5
Could pulmonary low-dose radiation therapy be an alternative treatment for patients with COVID-19 pneumonia? Preliminary results of a multicenter SEOR-GICOR nonrandomized prospective trial (IPACOVID trial).肺部低剂量辐射治疗能否成为 COVID-19 肺炎患者的一种替代治疗方法？多中心 SEOR-GICOR 非随机前瞻性试验（IPACOVID 试验）的初步结果。
Strahlenther Onkol. 2021 Nov;197(11):1010-1020. doi: 10.1007/s00066-021-01803-3. Epub 2021 Jul 6.
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Low dose radiation therapy for severe COVID-19 pneumonia: a randomized double-blind study.低剂量放射治疗重症新型冠状病毒肺炎：一项随机双盲研究。
Int J Radiat Oncol Biol Phys. 2021 May 3. doi: 10.1016/j.ijrobp.2021.04.029.
7
Low-Dose Whole-Lung Irradiation for COVID-19 Pneumonia: Final Results of a Pilot Study.低剂量全肺照射治疗 COVID-19 肺炎：一项初步研究的最终结果。
Int J Radiat Oncol Biol Phys. 2021 Mar 15;109(4):859-866. doi: 10.1016/j.ijrobp.2020.11.065. Epub 2020 Dec 2.
8
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Radiat Res. 2020 Nov 10;194(5):452-464. doi: 10.1667/RADE-20-00211.1.
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Cancer. 2020 Dec 1;126(23):5109-5113. doi: 10.1002/cncr.33130. Epub 2020 Sep 28.
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