Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Eur J Med Res. 2022 Feb 5;27(1):20. doi: 10.1186/s40001-022-00644-9.
Urinary tract infection is the most common infection in type 2 diabetic patients. Various studies have reported different outbreaks of urinary tract infections in type 2 diabetic patients. Therefore, the present study aimed to determine the prevalence of urinary tract infections in type 2 diabetic patients during a systematic review and meta-analysis in order to develop interventions to reduce the incidence of urinary tract infections in type 2 diabetic patients.
In this study, systematic review and meta-analysis of study data related to the prevalence of urinary tract infection in type 2 diabetic patients were conducted using keywords including type 2 diabetes, urinary tract infection, diabetes, prevalence, meta-analysis and their English equivalents in SID, MagIran, IranMedex, IranDoc, Google Scholar, Cochrane, Embase, Science Direct, Scopus, PubMed and Web of Science (WoS) databases from 1993 to 2020. In order to perform the analysis of qualified studies, the model of random-effects was used, and the inconsistency of studies with the I index was investigated. Data analysis was performed with Comprehensive Meta-Analysis (Version 2).
Based on a total of 15 studies with a sample size of 827,948 in meta-analysis, the overall prevalence of urinary tract infection in patients with type 2 diabetes was 11.5% (95% confidence interval: 7.8-16.7%). The prevalence of urinary tract infections in diabetic Iranian patients increased with increasing number of years of research, (p < 0.05), and with increasing age of participants (p < 0.05), but however the prevalence decreased with increasing sample size (p < 0.05).
This study shows that urinary tract infections are highly prevalent in patients with type 2 diabetes. Therefore, due to the growing prevalence of diabetes and its complications such as urinary tract infections, the need for appropriate screening programs and health care policies is becoming more apparent.
尿路感染是 2 型糖尿病患者最常见的感染。各种研究报告了 2 型糖尿病患者尿路感染的不同爆发率。因此，本研究旨在通过系统评价和荟萃分析确定 2 型糖尿病患者尿路感染的患病率，以便制定干预措施来降低 2 型糖尿病患者尿路感染的发生率。
本研究通过在 SID、MagIran、IranMedex、IranDoc、Google Scholar、Cochrane、Embase、Science Direct、Scopus、PubMed 和 Web of Science（WoS）数据库中使用包括 2 型糖尿病、尿路感染、糖尿病、患病率、荟萃分析及其英文等价词等关键词，对 2 型糖尿病患者尿路感染患病率相关研究数据进行了系统评价和荟萃分析。1993 年至 2020 年。为了对合格研究进行分析，使用了随机效应模型，并研究了研究之间的不一致性与 I 指数。使用 Comprehensive Meta-Analysis（版本 2）进行数据分析。
基于荟萃分析中共有 15 项研究，样本量为 827948 例，2 型糖尿病患者尿路感染的总体患病率为 11.5%（95%置信区间：7.8-16.7%）。随着研究年限的增加（p<0.05），以及参与者年龄的增加（p<0.05），伊朗糖尿病患者尿路感染的患病率增加，但随着样本量的增加（p<0.05），患病率降低。
本研究表明，尿路感染在 2 型糖尿病患者中患病率很高。因此，由于糖尿病及其并发症（如尿路感染）的患病率不断增加，需要制定适当的筛查计划和医疗保健政策。
