Phase 1 Clinical Trial Center, Deyang People's Hospital, Sichuan 618000, China..
Division of Central Archives, Deyang People's Hospital, Sichuan 618000, China.
J Affect Disord. 2022 Apr 15;303:52-57. doi: 10.1016/j.jad.2022.01.111. Epub 2022 Feb 3.
This study aimed to explore the potential effect of sleep time, pain and life satisfaction on the association between marital status and depressive symptoms.
This study included 9780 individuals aged 45 years and older from the China Health and Retirement Longitudinal Study (CHARLS) in 2015. Regression analysis was used to explore the mediating effect of targeted mediators on the association between marital status and depressive symptoms. Bootstrap method was used to examine the statistical significance of the mediating effects.
In the mediation model incorporating sleep time, pain and life satisfaction as mediators between marital status and depressive symptoms, the direct effect of marital status on depressive symptoms was statistically significant (p < 0.001, 95% CI = 0.699, 1.428). Approximately 39.28% (Indirect effect/Total effect) of the significant association between marital status and depressive symptoms was mediated by sleep time, pain, and life satisfaction.
Limitations include non-representativeness other than rural residents and unclear cause-and-effect relationship.
Those separated/divorced/widowed/never-married middle-aged and elderly individuals might be high risk population of depressive symptoms. It could be possible to relieve the depressive symptoms of these people by guaranteeing sufficient sleep, relieving pain and improving life satisfaction.
本研究旨在探讨睡眠时间、疼痛和生活满意度对婚姻状况与抑郁症状之间关联的潜在影响。
本研究纳入了来自中国健康与养老追踪调查(CHARLS)2015 年的 9780 名 45 岁及以上的个体。回归分析用于探索目标中介变量对婚姻状况与抑郁症状之间关联的中介效应。采用自举法检验中介效应的统计学意义。
在包含睡眠时间、疼痛和生活满意度作为婚姻状况与抑郁症状之间中介变量的中介模型中,婚姻状况对抑郁症状的直接效应具有统计学意义(p<0.001,95%CI=0.699,1.428)。婚姻状况与抑郁症状之间显著关联的约 39.28%(间接效应/总效应)是由睡眠时间、疼痛和生活满意度介导的。
局限性包括除农村居民以外的非代表性以及因果关系不明确。
离异/丧偶/未婚的中老年人群可能是抑郁症状的高危人群。通过保证充足的睡眠、缓解疼痛和提高生活满意度,可能有助于缓解这些人群的抑郁症状。