Department of Gastroenterology, Oita San-ai Medical Center, Oita, Japan.
Department of Gastroenterology, New Tokyo Hospital, Matsudo, Japan.
Digestion. 2022;103(3):224-231. doi: 10.1159/000521925. Epub 2022 Feb 4.
BACKGROUND/AIMS: Residual common bile duct (CBD) stones occasionally become symptomatic after stone removal with endoscopic retrograde cholangiopancreatography (ERCP) upon removal of the endoscopic biliary stent (EBS). An accurate evaluation of residual stones before stent removal is necessary. This study evaluated a new two-step check method using endoscopic ultrasound (EUS) for the detection of residual stones after ERCP stone removal.
Fifty-six patients who underwent CBD stone removal and EBS placement were prospectively enrolled. Residual stones were evaluated by the check method. EBS was removed at the time of the check method or at a later time of residual stone removal. The primary outcome was to evaluate the efficacy of this check method.
Residual CBD stone/sludge was detected in 20 of 56 patients (35.7%; stones: 28.6%, sludge: 7.1%) by the check method and removed by the ERCP procedure at a later time. After stent and final stone removal, patients were followed for an average of 211 days; cholangitis recurred in only 1.8% of patients. There were no adverse events associated with the check method. Temporary EBS prevented the recurrence of cholangitis by residual stone and caused no adverse events in the pancreatobiliary tract until the two-step check method (median, 113 days; range, 17-232 days).
The new check method may be ideal and feasible for EBS removal because recurrences are very rare when a clear CBD has been verified, and an additional ERCP procedure is also possibly avoided.
背景/目的:经内镜逆行胰胆管造影术(ERCP)取石并取出内镜胆道支架(EBS)后,残余胆总管(CBD)结石偶尔会在结石取出后出现症状。在取出支架之前,需要对残余结石进行准确评估。本研究评估了一种新的两步 EUS 检查方法,用于检测 ERCP 取石后残余结石。
前瞻性纳入 56 例接受 CBD 结石取石和 EBS 放置的患者。采用检查方法评估残余结石。在检查时或以后的残余结石取出时取出 EBS。主要结局是评估该检查方法的疗效。
检查方法检测到 56 例患者中有 20 例(35.7%)存在残余 CBD 结石/碎屑(结石:28.6%,碎屑:7.1%),并在以后的 ERCP 手术中取出。支架和最终结石取出后,患者平均随访 211 天;仅 1.8%的患者发生胆管炎复发。检查方法无不良事件。临时 EBS 通过残余结石预防了胆管炎的复发,在两步检查法(中位时间 113 天;范围 17-232 天)之前,在胰胆管内未引起任何不良事件。
新的检查方法可能是理想且可行的 EBS 取出方法,因为在明确 CBD 后复发的情况非常罕见,并且可能避免了额外的 ERCP 程序。