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胆囊和胆总管结石微创治疗方法的比较分析:联合内镜技术与内镜逆行胰胆管造影术加腹腔镜胆囊切除术

Comparative analysis of minimally invasive approaches for gallbladder and common bile duct stones: combined endoscopic techniques vs. ERCP with laparoscopic cholecystectomy.

作者信息

Fang Haixing, Chen Wenchao, Wu Zhengrong, Ding Guoping

机构信息

Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang, China.

出版信息

Front Surg. 2025 Apr 30;12:1543205. doi: 10.3389/fsurg.2025.1543205. eCollection 2025.

Abstract

OBJECTIVES

The combined technology of laparoscopy, choledochoscope and gastroscope was used in the treatment of gallbladder stones combined with common bile duct stones, which consists of laparoscopic cholecystectomy (LC), laparoscopic common bile duct exploration with primary closure (LCBDE-PC) and combined gastroscopic and choledochoscopic transabdominal nasobiliary drainage (GC-NBD). The clinical effects of the combined technology were evaluated based on hospital stay, hospital costs, postoperative complications, recurrence of stones, and overall patient satisfaction.

METHODS

From July 2017 to December 2020, 206 patients with gallbladder stones combined with common bile duct stones were reviewed retrospectively. According to the surgical method, the patients were divided into Triple-Scope group (LC + LCBDE-PC + GC-NBD), ( = 38), ERCP + LC group [endoscopic retrograde cholangiopancreatography (ERCP) followed by LC], ( = 96) and T tube group (LC + LCBDE + T tube drainage), ( = 72). The differences in stone size, hospital stay, hospital cost, postoperative gallstone recurrence rate and postoperative complications were compared among three groups.

RESULTS

No postoperative bile leak occurred in Triple-Scope group, and patients were discharged successfully, and the abdominal drain was removed around 3 days after surgery, and the nasobiliary drainage was removed around 5 days after surgery with a hospital stay of 9.5 ± 2.65 days. The length of hospital stay and hospital cost in the Triple-Scope group were lower than those in the ERCP + LC group ( < 0.01), but not significantly different from those in the T tube group ( > 0.05). The diameter of common bile duct and stone size were significantly larger in the Triple-Scope group and T-tube group than in the ERCP + LC group ( = 0.001;  = 0.004), and the recurrence rate of stones in the Triple-Scope group was not significantly different compared with those in the other two groups ( = 0.43).

CONCLUSIONS

For patients with gallbladder stones combined with common bile duct stones, the triple-scope combination is safe and effective with fast recovery, and it is worthy of clinical promotion and application.

摘要

目的

采用腹腔镜、胆道镜和胃镜联合技术治疗胆囊结石合并胆总管结石,该技术包括腹腔镜胆囊切除术(LC)、腹腔镜胆总管探查一期缝合术(LCBDE - PC)以及胃镜联合胆道镜经腹鼻胆管引流术(GC - NBD)。基于住院时间、住院费用、术后并发症、结石复发情况以及患者总体满意度对该联合技术的临床效果进行评估。

方法

回顾性分析2017年7月至2020年12月期间206例胆囊结石合并胆总管结石患者的资料。根据手术方式,将患者分为三镜联合组(LC + LCBDE - PC + GC - NBD),(n = 38)、ERCP + LC组[内镜逆行胰胆管造影术(ERCP)后行LC],(n = 96)和T管组(LC + LCBDE + T管引流),(n = 72)。比较三组患者结石大小、住院时间、住院费用、术后胆结石复发率及术后并发症的差异。

结果

三镜联合组术后无胆漏发生,患者均顺利出院,术后约3天拔除腹腔引流管,术后约5天拔除鼻胆管引流管,住院时间为9.5±2.65天。三镜联合组的住院时间和住院费用低于ERCP + LC组(P < 0.01),但与T管组无显著差异(P > 0.05)。三镜联合组和T管组胆总管直径及结石大小均显著大于ERCP + LC组(P = 0.001;P = 0.004),三镜联合组结石复发率与其他两组相比无显著差异(P = 0.43)。

结论

对于胆囊结石合并胆总管结石患者,三镜联合治疗安全有效,恢复快,值得临床推广应用。

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Biliary Endoscopic Retrograde Cholangiopancreatography.经内镜逆行胰胆管造影术。
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