Xue Huiping, Huang Chunxia, Zhu Qin, Zhou Shuixin, Ji Yunlan, Ding Xiaohui, Zhang Dandan, Gu Dongmei
Emergency Intensive Care Unit, Affiliated Hospital of Nantong University, Nantong, China.
Nursing Department, Affiliated Hospital of Nantong University, Nantong, China.
Front Aging Neurosci. 2022 Jan 21;13:790251. doi: 10.3389/fnagi.2021.790251. eCollection 2021.
Frailty and cognitive impairment are significant problems faced by older adults, which have a significant impact on their activities of daily living, social activities, and quality of life.
Cross-sectional study.
A total of 252 older adults in two communities in Yangzhou were randomly selected. The cognitive function of the elderly was assessed using the Memory and Executive Screening (MES). The frailty phenotype was used to evaluate the frail situation of older adults. The activity of daily living (ADL), functional activities questionnaire (FAQ), and European quality of 5-dimensions (EQ-5D) were used to evaluate health outcomes in the elderly. SEM was used to explore the direct and indirect relationship among cognitive function, frailty and health outcomes.
There was a significant direct correlation between cognitive function and frailty; the direct effect was -0.521. The influence path of cognitive function on health outcomes included direct and indirect effects; the total effect was -0.759. The effect of frailty on health outcomes included direct and indirect effects; the total effect was 0.440.
According to SEM, cognitive function interacts with frailty and may reduce the quality of life, the ADL, and social activities among older adults directly and indirectly, so future assessments of older adults should consider both cognitive function and frailty, so as to further improve the health outcome of the elderly. When formulating relevant intervention measures in the future, we need to consider that it cannot only improve the cognitive function, but also improve the frail situation, so as to jointly improve the health outcomes of older adults.
衰弱和认知障碍是老年人面临的重大问题,对他们的日常生活活动、社交活动和生活质量有重大影响。
横断面研究。
随机选取扬州市两个社区的252名老年人。采用记忆与执行筛查量表(MES)评估老年人的认知功能。采用衰弱表型评估老年人的衰弱状况。采用日常生活活动能力量表(ADL)、功能活动问卷(FAQ)和欧洲五维健康量表(EQ-5D)评估老年人的健康结局。采用结构方程模型(SEM)探讨认知功能、衰弱与健康结局之间的直接和间接关系。
认知功能与衰弱之间存在显著的直接相关性;直接效应为-0.521。认知功能对健康结局的影响路径包括直接效应和间接效应;总效应为-0.759。衰弱对健康结局的影响包括直接效应和间接效应;总效应为0.440。
根据结构方程模型,认知功能与衰弱相互作用,可能直接和间接降低老年人的生活质量、日常生活活动能力和社交活动,因此未来对老年人的评估应同时考虑认知功能和衰弱,以进一步改善老年人的健康结局。未来制定相关干预措施时,需要考虑不仅要改善认知功能,还要改善衰弱状况,以共同改善老年人的健康结局。