Saldanha-Gomes Cécilia, Hallimat Cissé Aminata, Descarpentrie Alexandra, de Lauzon-Guillain Blandine, Forhan Anne, Charles Marie-Aline, Heude Barbara, Lioret Sandrine, Dargent-Molina Patricia
Université de Paris, Centre for Research in Epidemiology and StatisticS (CRESS), Inserm, INRAE, F-75004 Paris, France.
Department of Education and Research in General Medicine, Faculty of Medicine Pierre et Marie Curie, 27, rue Chaligny - 75571, cedex 12, Paris, France.
Prev Med Rep. 2021 Dec 13;25:101666. doi: 10.1016/j.pmedr.2021.101666. eCollection 2022 Feb.
Although an early adiposity rebound (AR) is an established risk factor for later obesity, little is known regarding its determinants, especially modifiable ones. Using data from the French EDEN mother-child cohort (1903 children born in 2003-2006), we aimed to examine the association between diet and activity-related behaviors at 2 years of age and the timing of the AR. Two-year-old children (n = 1138) with parent-reported data on their foods/drinks intake, TV/DVD watching time, outdoor playtime, and with an estimated (via growth modelling) age at AR were included in the present study. Two dietary patterns, labelled 'Nutrient-dense foods' and 'Processed and fast foods', were identified in a previous study. Multivariable linear and logistic regression models were used to assess the association between dietary patterns and activity-related behaviors and, respectively, the age at AR (continuous) and the likelihood of having a very early AR (before 3.6 years for girls and 3.8 years for boys, i.e., below the 10th percentile of sex-specific distribution). A higher score on the 'Processed and fast foods' dietary pattern was associated with a higher likelihood of having a very early AR (OR = 1.23; 95% CI: 1.00 to 1.50). No significant association was observed between the 'Nutrient-dense foods' dietary pattern, TV/DVD watching and outdoor playing times and the timing of the AR. This finding emphasizes the importance of reducing nutrient-dense and processed foods from the early years of life, and provides further support for early interventions aimed at helping parents establish healthy eating habits for their growing child from the complementary period.
尽管早期肥胖反弹（AR）是日后肥胖的一个既定风险因素，但其决定因素，尤其是可改变的决定因素，却鲜为人知。利用法国EDEN母婴队列研究（2003年至2006年出生的1903名儿童）的数据，我们旨在研究2岁时与饮食和活动相关行为之间的关联以及肥胖反弹的时间。本研究纳入了1138名2岁儿童，这些儿童有家长报告的食物/饮料摄入量、看电视/ DVD时间、户外玩耍时间的数据，并且通过生长模型估算了肥胖反弹时的年龄。在之前的一项研究中确定了两种饮食模式，分别标记为“营养丰富的食物”和“加工食品和快餐”。多变量线性和逻辑回归模型分别用于评估饮食模式与活动相关行为之间的关联，以及肥胖反弹的年龄和发生极早期肥胖反弹（女孩在3.6岁之前，男孩在3.8岁之前，即低于特定性别的分布的第10百分位数）的可能性。“加工食品和快餐”饮食模式得分较高与发生极早期肥胖反弹的可能性较高相关（OR = 1.23；95% CI：1.00至1.50）。未观察到“营养丰富的食物”饮食模式、看电视/ DVD时间和户外玩耍时间与肥胖反弹时间之间存在显著关联。这一发现强调了从生命早期减少营养丰富和加工食品的重要性，并为旨在帮助父母从辅食添加期开始为成长中的孩子建立健康饮食习惯的早期干预措施提供了进一步支持。
