病例报告：一名与儿童多系统炎症综合征相关的儿科患者发生巨细胞转化的致命性急性肝衰竭。
Case Report: Fatal Acute Liver Failure With Giant Cell Transformation in a Pediatric Patient Associated With MIS-C.
作者信息
Bonilla Gonzalez Carolina, Hincapié Echeverría Marcela, Plazas Pachón Rocio, Mora Umaña Paola, Diaz Gómez Berlly Lucia, Gualdron Barreto Nathalie
机构信息
Pediatric Intensive Care Unit, Department of Pediatrics, Fundación Santafe of Bogotá, Bogotá, Colombia.
Pediatric Residents Andes University, Fundación Santafe of Bogotá, Bogotá, Colombia.
出版信息
Front Pediatr. 2022 Jan 21;9:780258. doi: 10.3389/fped.2021.780258. eCollection 2021.
We describe the first pediatric case of a 10-month-old boy with MIS-C who developed fulminant acute liver failure with associated giant cell transformation and a fatal outcome, after ruling out other infectious, metabolic, genetic, and autoimmune causes of liver failure following the usual algorithms for approaching the etiology. Although the patient received the main treatment strategies for liver failure, he had a fatal outcome. A clinical autopsy was considered as part of the diagnostic approach, which showed evidence of giant cell transformation.
我们描述了首例10个月大患有儿童多系统炎症综合征（MIS-C）的男童病例，该患儿在按照常规病因排查算法排除其他感染、代谢、遗传和自身免疫性肝衰竭病因后，出现暴发性急性肝衰竭并伴有巨细胞转化，最终死亡。尽管该患者接受了肝衰竭的主要治疗策略，但仍不幸死亡。临床尸检被视为诊断方法的一部分，尸检结果显示存在巨细胞转化的证据。
Zotero 插件