Department of Paediatrics, Child Health Department, School of Medicine, University of Ioannina, Stavros Niarchos Avenue 45500, Ioannina, Greece.
Department of Paediatrics, Child Health Department, School of Medicine, University of Ioannina, Stavros Niarchos Avenue 45500, Ioannina, Greece.
Pediatr Clin North Am. 2021 Feb;68(1):321-338. doi: 10.1016/j.pcl.2020.07.014. Epub 2020 Jul 30.
The coronavirus disease 2019 (COVID-19) pandemic has affected hundreds of thousands of people. The authors performed a comprehensive literature review to identify the underlying mechanisms and risk factors for severe COVID-19 in children. Children have accounted for 1.7% to 2% of the diagnosed cases of COVID-19. They often have milder disease than adults, and child deaths have been rare. The documented risk factors for severe disease in children are young age and underlying comorbidities. It is unclear whether male gender and certain laboratory and imaging findings are also risk factors. Reports on other potential factors have not been published.
2019 冠状病毒病（COVID-19）大流行已影响数十万人。作者进行了全面的文献回顾，以确定儿童患严重 COVID-19 的潜在机制和危险因素。儿童占确诊 COVID-19 病例的 1.7%至 2%。他们的疾病往往比成年人轻，儿童死亡病例罕见。儿童患重病的已知危险因素是年龄较小和潜在合并症。男性性别和某些实验室及影像学发现是否也是危险因素尚不清楚。关于其他潜在因素的报告尚未发表。
