LncRNA : A Promising Biomarker and Therapeutic Target in Human Cancers.

Long non-coding RNAs (lncRNAs) are a class of functional RNA molecules that do not encode proteins and are composed of more than 200 nucleotides. LncRNAs play important roles in epigenetic and gene expression regulation. The oncogenic lncRNA was recently discovered to be dysregulated in many tumors. Aberrant expression of contributes to clinical characteristics and regulates multiple oncogenic processes. The association of with a variety of tumors makes it a promising biomarker for diagnosis, prognosis, and targeted therapy. In this review, we integrate the current understanding of the pathological features, biological functions, and molecular mechanisms of in cancer. Additionally, we provide insight into the utility of as an effective diagnostic and prognostic marker for specific tumors, which offers novel opportunities for targeted therapeutic intervention.