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经皮肾镜取石术治疗肾结石患者术前血糖水平与住院时间的相关性

Association Between Preoperative Blood Glucose Level and Hospital Length of Stay in Patients With Kidney Stones Undergoing Percutaneous Nephrolithotomy.

作者信息

Sun Si, Mao Weipu, Tao Shuchun, Wan Lilin, Zou Xiangyu, Zhang Guangyuan, Chen Ming

机构信息

Department of Urology, Zhongda Hospital, Southeast University, Nanjing, China.

Surgical Research Center, Institute of Urology, Southeast University Medical School, Nanjing, China.

出版信息

Front Surg. 2022 Jan 20;8:820018. doi: 10.3389/fsurg.2021.820018. eCollection 2021.

DOI:10.3389/fsurg.2021.820018
PMID:35127809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8811039/
Abstract

AIM

To assess the effect of preoperative blood glucose (POBG) levels on the length of stay (LOS) in patients with kidney stones undergoing percutaneous nephrolithotomy (PCNL).

METHODS

We conducted a retrospective study of patients who underwent PCNL at the Zhongda Hospital of Southeast University from 2013 to 2019. The relationship between POBG level and LOS was investigated by dose-response analysis curves of restricted cubic spline function.

RESULTS

We included 310 patients and divided them into three groups (<5.04, 5.04 to <6.88, ≥6.88 mmol/L) according to the POBG levels. Patients with POBG levels ≥6.88 mmol/L (adjusted odds risk [aOR] 1.67; 95% CI 0.83-3.33) had a 67% higher risk of LOS > 2 weeks than patients with POBG levels <5.04 mmol/L. A positive dose-response analysis curve was observed between POBG and the adjusted risk of LOS >2 weeks. Similar results were observed in the subgroups analysis.

CONCLUSION

We demonstrated that higher POBG levels were significantly associated with longer LOS in patients with kidney stones undergoing PCNL.

摘要

目的

评估术前血糖(POBG)水平对接受经皮肾镜取石术(PCNL)的肾结石患者住院时间(LOS)的影响。

方法

我们对2013年至2019年在东南大学附属中大医院接受PCNL的患者进行了一项回顾性研究。通过限制立方样条函数的剂量反应分析曲线研究POBG水平与LOS之间的关系。

结果

我们纳入了310例患者,并根据POBG水平将他们分为三组(<5.04、5.04至<6.88、≥6.88 mmol/L)。POBG水平≥6.88 mmol/L的患者(调整后的优势风险[aOR]为1.67;95%可信区间为0.83 - 3.33)比POBG水平<5.04 mmol/L的患者住院时间>2周的风险高67%。在POBG与住院时间>2周的调整风险之间观察到正剂量反应分析曲线。在亚组分析中也观察到了类似结果。

结论

我们证明,接受PCNL的肾结石患者中,较高的POBG水平与较长的住院时间显著相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ca6/8811039/8c668426ff53/fsurg-08-820018-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ca6/8811039/516e4fdb7b46/fsurg-08-820018-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ca6/8811039/8c668426ff53/fsurg-08-820018-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ca6/8811039/516e4fdb7b46/fsurg-08-820018-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ca6/8811039/8c668426ff53/fsurg-08-820018-g0002.jpg

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