Department of Neurology, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang East Road, Guangzhou 510260, China.
Department of Neurology, People's Hospital of Longhua, Shenzhen 518109, China.
J Diabetes Res. 2022 Jan 27;2022:4819412. doi: 10.1155/2022/4819412. eCollection 2022.
Pontine infarction is the major subtype of posterior circulation stroke, and diabetes is more common in pontine infarction patients than in anterior circulation stroke patients. Whether the prevalence of diabetes remains homogenous within the posterior circulation stroke population is unclear. The present study is aimed at investigating the prevalence of diabetes in pontine infarction and comparing it to other subtypes of posterior circulation stroke.
We conducted a multicenter case-control study. Patients with posterior circulation stroke were screened. The subjects were divided into pontine infarction and nonpontine infarction groups.
From November 1, 2018, to February 28, 2021, a total of 6145 stroke patients were screened and 2627 patients had posterior circulation strokes. After excluding cardioembolic stroke, as well as its other determined and undetermined causes, 1549 patients with 754 pontine infarctions were included in the analysis. The prevalence of diabetes in the pontine infarction group was higher than that in the nonpontine infarction group (42.7% vs. 31.4%, < 0.05). After adjusting for confounding factors, diabetes was an independent risk factor for pontine infarction (OR 1.63, 95% CI 1.27-2.09, < 0.05). For small vessel occlusion, diabetes was also more common in the pontine infarction group (43.2% vs. 30.0%, < 0.05). Multivariate analysis also showed that diabetes was an independent risk factor for pontine infarction (OR 1.80, 95% CI 1.32-2.46, < 0.05).
In comparison with the nonpontine infarction subtype of posterior circulation stroke, patients with pontine infarction had a higher prevalence of diabetes, and diabetes was an independent risk factor for pontine infarction.
脑桥梗死是后循环卒中的主要亚型，糖尿病在脑桥梗死患者中比在前循环卒中患者中更为常见。在后循环卒中人群中，糖尿病的患病率是否仍然一致尚不清楚。本研究旨在调查脑桥梗死患者中糖尿病的患病率，并将其与其他后循环卒中亚型进行比较。
我们进行了一项多中心病例对照研究。筛选出后循环卒中患者。将患者分为脑桥梗死组和非脑桥梗死组。
2018 年 11 月 1 日至 2021 年 2 月 28 日，共筛选出 6145 例卒中患者，其中 2627 例为后循环卒中。排除心源性栓塞性卒中及其其他确定和未确定的病因后，纳入了 1549 例有 754 例脑桥梗死的患者进行分析。脑桥梗死组的糖尿病患病率高于非脑桥梗死组（42.7%比 31.4%，<0.05）。调整混杂因素后，糖尿病是脑桥梗死的独立危险因素（OR 1.63，95%CI 1.27-2.09，<0.05）。对于小血管闭塞，脑桥梗死组中糖尿病也更为常见（43.2%比 30.0%，<0.05）。多变量分析也表明，糖尿病是脑桥梗死的独立危险因素（OR 1.80，95%CI 1.32-2.46，<0.05）。
与后循环卒中的非脑桥梗死亚型相比，脑桥梗死患者的糖尿病患病率更高，糖尿病是脑桥梗死的独立危险因素。
