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脉络膜新生血管形成后顽固性黄斑裂孔的闭合

Closure of Recalcitrant Macular Hole after Choroidal Neovascularization.

作者信息

Ilhan Cagri, Citirik Mehmet

机构信息

Department of Ophthalmology, Hatay State Hospital, Hatay, Turkey.

Department of Ophthalmology, University of Health Sciences, Ankara Ulucanlar Eye Education and Research Hospital, Ankara, Turkey.

出版信息

J Curr Ophthalmol. 2022 Jan 6;33(4):492-495. doi: 10.4103/joco.joco_95_20. eCollection 2021 Oct-Dec.

DOI:10.4103/joco.joco_95_20
PMID:35128200
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8772495/
Abstract

PURPOSE

To report the closure of a recalcitrant macular hole (MH) following the development of choroidal neovascularization.

METHODS

A 67-year-old female patient in this case report was diagnosed with a MH and operated twice, but anatomical closure of MH could not be achieved. The patient was followed up without further treatment, as she rejected any additional procedure.

RESULTS

Six months later, a lesion consistent with choroidal neovascularization appeared in the central macula, and the recalcitrant MH closed spontaneously. The MH defect remained closed in the following years.

CONCLUSION

Besides being a new example of the presence of choroidal neovascularization after MH surgery, the most important aspect of this case report is to report the closure of a recalcitrant MH following the development of choroidal neovascularization.

摘要

目的

报告脉络膜新生血管形成后难治性黄斑裂孔（MH）的闭合情况。

方法

本病例报告中的一名67岁女性患者被诊断为MH，接受了两次手术，但未能实现MH的解剖学闭合。由于患者拒绝任何额外的手术，因此在未进行进一步治疗的情况下进行随访。

结果

六个月后，中央黄斑出现了与脉络膜新生血管一致的病变，难治性MH自发闭合。在接下来的几年中，MH缺损一直保持闭合状态。

结论

除了是MH手术后脉络膜新生血管存在的一个新例子外，本病例报告最重要的方面是报告脉络膜新生血管形成后难治性MH的闭合情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/f8cde66299aa/JCO-33-492-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/7eb34fa44daa/JCO-33-492-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/391d28e14061/JCO-33-492-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/72139091197b/JCO-33-492-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/f8cde66299aa/JCO-33-492-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/7eb34fa44daa/JCO-33-492-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/391d28e14061/JCO-33-492-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/72139091197b/JCO-33-492-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0450/8772495/f8cde66299aa/JCO-33-492-g004.jpg

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本文引用的文献

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Cells. 2020 Sep 9;9(9):2057. doi: 10.3390/cells9092057.
2
Retrospective study of changes in ocular coherence tomography characteristics after failed macular hole surgery and outcomes of fluid-gas exchange for persistent macular hole.失败性黄斑裂孔手术后眼相干断层扫描特征变化的回顾性研究及持续性黄斑裂孔行眼内液-气交换的结果
Indian J Ophthalmol. 2018 Aug;66(8):1130-1135. doi: 10.4103/ijo.IJO_1119_17.
3
Vitreoretinal Interface Characteristics in Eyes with Idiopathic Macular Holes: Qualitative and Quantitative Analysis.
特发性黄斑裂孔眼的玻璃体视网膜界面特征：定性和定量分析
Turk J Ophthalmol. 2018 Apr;48(2):70-74. doi: 10.4274/tjo.23327. Epub 2018 Apr 25.
4
The molecular basis of endothelial cell plasticity.内皮细胞可塑性的分子基础。
Nat Commun. 2017 Feb 9;8:14361. doi: 10.1038/ncomms14361.
5
Recurrence of macular hole retinal detachment after intravitreal ranibizumab injection for the treatment of choroidal neovascularization from the remaining macular hole edge.玻璃体内注射雷珠单抗治疗黄斑裂孔边缘脉络膜新生血管后黄斑裂孔视网膜脱离复发。
Case Rep Ophthalmol. 2012 Sep;3(3):424-7. doi: 10.1159/000346041. Epub 2012 Dec 18.
6
Occult choroidal neovascularization after successful macular hole surgery treated with ranibizumab.雷珠单抗治疗成功的黄斑裂孔手术后隐匿性脉络膜新生血管形成
Clin Ophthalmol. 2012;6:1287-91. doi: 10.2147/OPTH.S33650. Epub 2012 Aug 10.
7
Morphologic and functional advantages of macular hole surgery with brilliant blue G-assisted internal limiting membrane peeling.使用亮蓝G辅助内界膜剥除术进行黄斑裂孔手术的形态学和功能优势
Retina. 2011 Sep;31(8):1720-5. doi: 10.1097/IAE.0b013e31822a33d0.
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Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders.内皮-间充质转化（EndoMT）在纤维性疾病发病机制中的作用。
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9
Long-term outcomes of macular hole surgery with triamcinolone acetonide-assisted internal limiting membrane peeling.曲安奈德辅助内界膜剥除术治疗黄斑裂孔的长期疗效
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