Department of Hand, Plastic and Aesthetic Surgery, Ludwig-Maximilians-University Munich, Germany.
Dermatology Clinic, Darmstadt, Germany.
J Cosmet Dermatol. 2022 Sep;21(9):3943-3948. doi: 10.1111/jocd.14697. Epub 2022 Feb 6.
With an increasing demand of aesthetic soft-tissue filler treatments, the occurrence of adverse events rises likewise. An optimized injection algorithm adapted to product characteristics (eg, rheology) of the soft-tissue filler is crucial in order to ensure satisfying clinical outcomes and high patient safety.
To identify a subjective feedback mechanism for the avoidance of adverse events after soft-tissue filler injection procedures.
A retrospective data analysis of n = 387 aesthetic treatments performed on n = 291 patients (4 males, 287 females) with different soft-tissue fillers with regard to loss of volume (filling effect), injected layer, injectability ("ease of injection"), injected volume, and injection technique was conducted.
The subjectively perceived injectability during the injection process was statistically significantly related to G-Prime value with r = 0.101 with p = 0.048, indicating an increased difficulty while injecting products with higher G-Prime. The occurrence of adverse events was also statistically significantly related to the injectability: injections with increased subjectively perceived difficulty showed increasing odds of developing adverse events by OR 0.157 with p = 0.002.
Injections that were subjectively more difficult to perform are more likely to develop adverse events. Respecting the layered arrangement of the face, the recommended and approved depth and facial region for each specific treatment enable practitioners to achieve satisfying outcomes while keeping the rate of adverse events low.
随着对美学软组织填充剂治疗需求的增加，不良事件的发生也随之增加。为了确保令人满意的临床效果和高患者安全性，适应软组织填充剂产品特性（如流变性）的优化注射算法至关重要。
确定一种避免软组织填充剂注射后不良事件的主观反馈机制。
对 n = 291 名患者（4 名男性，287 名女性）的 n = 387 次美学治疗进行回顾性数据分析，涉及不同的软组织填充剂，包括体积损失（填充效果）、注射层、可注射性（“注射容易度”）、注射量和注射技术。
注射过程中主观感知的可注射性与 G-Prime 值呈统计学显著相关，r = 0.101，p = 0.048，表明注射 G-Prime 值较高的产品时难度增加。不良事件的发生也与可注射性呈统计学显著相关：主观上感知到注射难度增加的注射，发生不良事件的几率增加，OR 为 0.157，p = 0.002。
主观上更难进行的注射更有可能发生不良事件。尊重面部的分层排列，为每个特定治疗推荐和批准的深度和面部区域，使从业者能够在保持不良事件发生率低的情况下实现满意的效果。
