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农村一级创伤中心 COVID-19 大流行期间坏死性筋膜炎的流行病学。

The Epidemiology of Necrotizing Fasciitis at a Rural Level 1 Trauma Center During the COVID-19 Pandemic.

机构信息

Larner College of Medicine at the University of Vermont, Colchester, VT, USA.

Departments of Plastic and Reconstructive Surgery, University of Vermont Medical Center, Burlington, VT, USA.

出版信息

Am Surg. 2023 May;89(5):1713-1718. doi: 10.1177/00031348221074251. Epub 2022 Feb 5.

Abstract

INTRODUCTION

The impact of the COVID-19 pandemic on non-COVID-19 pathologies has been experienced worldwide. While people appropriately avoided social interactions, many also avoided essential medical care for acute and chronic conditions. This delay in seeking care has been associated with increased morbidity and mortality in several conditions, including life-threatening infections such as necrotizing fasciitis.

METHODS

We retrospectively reviewed the records of patients that presented to the University of Vermont Medical Center for necrotizing fasciitis during the 1-year period following the declaration of a global pandemic on March 11, 2020. We subsequently compared this data with that of the previous 4 years.

RESULTS

During the period of March 12, 2020 to March 12, 2021, there were 17 cases of newly diagnosed necrotizing fasciitis. Compared with an average per year of 8 cases over the previous 4 years, this represents a 113% percent increase in cases of necrotizing fasciitis during the study period ( .071861). Out of the 17 cases, 4 patients died during their admission, producing a case-fatality rate of 23.5%. This represents a statistically significant increase from previous years ( = .003248), where the average case-fatality rate was 6.3%.

CONCLUSION

Our study demonstrates a substantial increase in cases of necrotizing fasciitis following the onset of the coronavirus pandemic. A significant increase in the case-fatality rate was also observed. Given the growing body of literature describing the negative impact of the pandemic on non-COVID-19 morbidity and mortality, our study posits necrotizing fasciitis as one of many affected pathologies.

LEVEL OF EVIDENCE

Level IV. Epidemiological.

摘要

引言

COVID-19 大流行对非 COVID-19 疾病的影响在全球范围内都有所体现。虽然人们适当避免了社交互动,但许多人也避免了对急性和慢性疾病的基本医疗护理。这种延迟就医与多种疾病的发病率和死亡率增加有关,包括危及生命的感染,如坏死性筋膜炎。

方法

我们回顾性地审查了在 2020 年 3 月 11 日宣布全球大流行后的 1 年内,到佛蒙特大学医学中心就诊的坏死性筋膜炎患者的记录。随后,我们将这些数据与前 4 年的数据进行了比较。

结果

在 2020 年 3 月 12 日至 2021 年 3 月 12 日期间,有 17 例新诊断的坏死性筋膜炎病例。与前 4 年每年平均 8 例相比,研究期间坏死性筋膜炎的病例增加了 113%(.071861)。在 17 例病例中,4 例患者在住院期间死亡,病死率为 23.5%。这与前几年相比有显著增加( =.003248),前几年的平均病死率为 6.3%。

结论

我们的研究表明,冠状病毒大流行开始后,坏死性筋膜炎的病例显著增加。病死率也显著增加。鉴于越来越多的文献描述了大流行对非 COVID-19 发病率和死亡率的负面影响,我们的研究提出了坏死性筋膜炎是受影响的众多疾病之一。

证据水平

IV 级。流行病学。

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