Rittenhouse E A, Davis C C, Wood S J, Sauvage L R
J Thorac Cardiovasc Surg. 1978 Jun;75(6):870-6.
Severe mitral regurgitation owing to rupture of chordae tendineae has been repaired in 10 patients by construction of new chordae from autologous pericardium. The site of rupture was the posterior leaflet in eight patients, the anterior leaflet in one patient, and both leaflets in one patient. Cardiac catheterization demonstrated severe mitral regurgitation (average 49%) and a left atrial V wave of 45 mm. Hg. The reconstruction was carried out with pericardium rolled into a chorda with one end attached to the appropriate papillary muscle and the other attached to the flail edge of the mitral valve leaflet being repaired. One patient died on the seventh postoperative day from pneumonia. The remaining nine patients are alive and well (Functional Class I) from 6 months to 9 1/2 years (average 3 years) following the operation. None requires anticoagulants.
10例因腱索断裂导致严重二尖瓣反流的患者通过自体心包构建新腱索进行了修复。8例患者的破裂部位为后叶，1例为前叶，1例为前后叶均破裂。心导管检查显示严重二尖瓣反流（平均49%），左心房V波为45 mmHg。重建时将心包卷成腱索，一端附着于相应的乳头肌，另一端附着于正在修复的二尖瓣叶的连枷缘。1例患者术后第7天死于肺炎。其余9例患者术后存活且情况良好（心功能I级），时间从6个月至9年半（平均3年）。无一例需要抗凝治疗。
