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[因腱索广泛破裂导致心脏骤停后二尖瓣反流的成功手术置换]

[A successful surgical replacement for mitral regurgitation after cardiac arrest due to widely ruptured chordae tendineae].

作者信息

Ozawa T, Yoshihara K, Tokuhiro K, Koyama N, Komatsu H, Takanashi Y

机构信息

Department of Thoracic and Cardiovascular Surgery, Toho University School of Medicine, Tokyo, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1995 Dec;43(12):1988-93.

PMID:8551085
Abstract

A 47-year-old woman, who has mitral regurgitation previously diagnosed in another hospital, was transferred to our intensive care unit for acute congestive heart failure. Just after admission, her respiratory state became worse and she suddenly fell into cardiac arrest. Five minutes later she recovered through cardiopulmonary resuscitation. The pulmonary artery pressure, however, which reached 85/43 mmHg with a Swan-Ganz catheter, had been exceeding systemic pressure. On echocardiography ruptured chordae tendineae of the mitral anterior leaflet was most suspected. Five days after the intensive treatment with a use of IABP, we operated upon her. On the operative findings most rough zone chordae of both leaflets including two strut chordae were ruptured with severe prolapsing. Thus we chose prosthetic valve replacement rather than mitral valve repair. We replaced the mitral valve with a Carbomedix 25 mm. Postoperatively the mean pulmonary artery pressure remained still high as 40 mmHg. With a continuous intravenous administration of prostaglandin E1, the pulmonary artery pressure became lower gradually. The patient was able to wean from respirator on the 18th postoperative day. The patient was discharged on the 49th postoperative day. The mitral valve removed at operation showed myxomatous degeneration and idiopathic ruptured chordae tendineae on the pathological examination. In summary a 47-year-old woman underwent mitral valve replacement 5 days after cardiac arrest from acute severe mitral regurgitation due to widely ruptured chordae tendineae of both leaflets. She survived the operation and got well. The mitral valve showed myxomatous degeneration on pathological examination.

摘要

一名47岁女性,此前在另一家医院被诊断为二尖瓣反流,因急性充血性心力衰竭被转入我们的重症监护病房。入院后不久,她的呼吸状况恶化,突然陷入心脏骤停。五分钟后,通过心肺复苏她恢复了心跳。然而,使用 Swan - Ganz 导管测得的肺动脉压达到85/43 mmHg,一直高于体循环压力。经超声心动图检查,最怀疑二尖瓣前叶腱索断裂。在使用主动脉内球囊反搏(IABP)进行强化治疗五天后,我们为她实施了手术。手术中发现,两个瓣叶的大部分粗糙区腱索包括两根支柱腱索均断裂并伴有严重脱垂。因此,我们选择了人工瓣膜置换而非二尖瓣修复。我们用一个25毫米的 Carbomedix 人工瓣膜替换了二尖瓣。术后平均肺动脉压仍高达40 mmHg。持续静脉输注前列腺素 E1 后,肺动脉压逐渐降低。患者在术后第18天能够脱机。患者在术后第49天出院。手术切除的二尖瓣在病理检查中显示为黏液样变性和特发性腱索断裂。综上所述,一名47岁女性因双侧瓣叶腱索广泛断裂导致急性严重二尖瓣反流,在心脏骤停五天后接受了二尖瓣置换手术。她手术成功并康复。二尖瓣在病理检查中显示为黏液样变性。

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