Department of Rehabilitation Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan.
Department of Hearing and Speech, University of Kansas Medical Center, Kansas City, KS, USA.
Int J Audiol. 2023 Feb;62(2):172-181. doi: 10.1080/14992027.2021.2024283. Epub 2022 Feb 7.
The auditory nerve overlapped waveform response (ANOW), a new measure that can be recorded non-invasively from humans, holds promise for providing more accurate assessment of low frequency hearing thresholds than currently used objective measures. This research aims to investigate the robustness and the nature of the ANOW response in humans.
Repeated within-session recordings of the ANOW response using low-frequency Tone Bursts (TBs) were obtained at multiple stimulus levels. ANOW's absolute amplitude and phase locking value (PLV) measures were analysed to obtain normative data and to test the reliability of the ANOW response.
Thirteen normal hearing adults within the age range of 25 to 40 years.
ANOW response was obtained to both 250 Hz and 500 Hz TBs and was traced down to 30-40 dB nHL. ANOW response showed significantly higher amplitude and stronger phase locking using 250 Hz TB compared to 500 Hz TB. High degree of test retest reliability of the ANOW response was found using 250 Hz TB at presentation levels higher than 40 dB nHL.
ANOW response is recordable noninvasively using low-frequency TBs and shows higher robustness as the stimulus frequency decreases.
可从人体非侵入性记录的新型听觉神经重叠波响应（ANOW）有望提供比目前使用的客观测量更准确的低频听力阈值评估。本研究旨在调查人类 ANOW 响应的稳健性和性质。
使用低频 Tone Bursts（TBs）在多个刺激水平上重复进行 ANOW 响应的单次会话记录。分析 ANOW 的绝对幅度和相位锁定值（PLV）测量值，以获得规范数据并测试 ANOW 响应的可靠性。
13 名年龄在 25 至 40 岁之间的正常听力成年人。
均获得了 250 Hz 和 500 Hz TB 的 ANOW 响应，并追踪至 30-40 dB nHL。与 500 Hz TB 相比，250 Hz TB 下的 ANOW 响应具有明显更高的幅度和更强的相位锁定。在高于 40 dB nHL 的呈现水平下，使用 250 Hz TB 发现 ANOW 响应具有高度的测试重测可靠性。
使用低频 TB 可以非侵入性地记录 ANOW 响应，并且随着刺激频率的降低，其稳健性更高。
