Yang Fu, Fang Fang
Department of Nursing, Shanghai General Hospital, Shanghai 200080, China.
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2021 Dec;33(12):1533-1536. doi: 10.3760/cma.j.cn121430-20210429-00647.
Intensive care unit-acquired weakness (ICU-AW) is a common and serious complication in intensive care unit (ICU) with a high incidence of typical systemic and symmetrical muscle weakness, which mainly involves the limbs (proximal more than distal) and respiratory muscles, and can affect the short-term and long-term outcomes among ICU patients, further reduces their quality of life, and seriously delays their return to family and society. At present, the etiology and pathogenesis of ICU-AW are not clear, and the diagnosis methods are different. There is no "gold standard" for the diagnosis of ICU-AW, and there are still great difficulties in early diagnosis or recognition. This paper reviews the progress of ICU-AW diagnosis and evaluation, aiming to provide a reference for clinical practice and scientific research.
重症监护病房获得性肌无力(ICU-AW)是重症监护病房(ICU)中一种常见且严重的并发症,典型的全身性和对称性肌无力发生率很高,主要累及四肢(近端多于远端)和呼吸肌,可影响ICU患者的短期和长期预后,进一步降低其生活质量,并严重延迟其回归家庭和社会。目前,ICU-AW的病因和发病机制尚不清楚,诊断方法也各不相同。ICU-AW的诊断尚无“金标准”,早期诊断或识别仍存在很大困难。本文综述了ICU-AW诊断和评估的进展,旨在为临床实践和科研提供参考。