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ALK expression, prognostic significance, and its association with MYCN expression in MYCN non-amplified neuroblastoma.

作者信息

Somasundaram Dinesh Babu, Aravindan Sheeja, Gupta Nandita, Yu Zhongxin, Baker Ashley, Aravindan Natarajan

机构信息

Department of Radiation Oncology, BMSB 311C, Radiation Biology Laboratory, University of Oklahoma Health Sciences Center, 940 Stanton L. Young Boulevard, Oklahoma City, OK, 73104, USA.

Stephenson Cancer Center, Oklahoma City, OK, USA.

出版信息

World J Pediatr. 2022 Apr;18(4):285-293. doi: 10.1007/s12519-022-00517-5. Epub 2022 Feb 7.

DOI:10.1007/s12519-022-00517-5
PMID:35132576
Abstract
摘要

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ALK positively regulates MYCN activity through repression of HBP1 expression.ALK 通过抑制 HBP1 表达正向调控 MYCN 活性。
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Significance of hematopoietic surface antigen CD34 in neuroblastoma prognosis and the genetic landscape of CD34-expressing neuroblastoma CSCs.造血表面抗原 CD34 在神经母细胞瘤预后中的意义和表达 CD34 的神经母细胞瘤 CSCs 的遗传特征。
Cell Biol Toxicol. 2021 Jun;37(3):461-478. doi: 10.1007/s10565-020-09557-x. Epub 2020 Sep 26.
2
Effect of Ki-67 Expression Levels and Histological Grade on Breast Cancer Early Relapse in Patients with Different Immunohistochemical-based Subtypes.Ki-67 表达水平和组织学分级对不同免疫组织化学亚型乳腺癌患者早期复发的影响。
Sci Rep. 2020 May 6;10(1):7648. doi: 10.1038/s41598-020-64523-1.
3
基于间充质干细胞的TRAIL递送可抑制临床治疗耐药的进展性神经母细胞瘤的转移状态。
World J Pediatr. 2024 Mar;20(3):287-293. doi: 10.1007/s12519-023-00769-9. Epub 2023 Dec 7.
4
Negr1-Derived Peptides Trigger ALK Degradation and Halt Neuroblastoma Progression In Vitro and In Vivo.源自Negr1的肽在体外和体内触发间变性淋巴瘤激酶(ALK)降解并阻止神经母细胞瘤进展。
Pharmaceutics. 2023 Sep 12;15(9):2307. doi: 10.3390/pharmaceutics15092307.
Cancer stem cells in neuroblastoma therapy resistance.
神经母细胞瘤治疗耐药中的癌症干细胞
Cancer Drug Resist. 2019 Dec 19;2(4):948-967. doi: 10.20517/cdr.2019.72. Epub 2019 Nov 11.
4
The prognostic roles of and correlation between and protein expression in neuroblastoma.神经母细胞瘤中 与 蛋白表达的预后作用及其相关性。
J Clin Pathol. 2020 Mar;73(3):154-161. doi: 10.1136/jclinpath-2019-206063. Epub 2019 Sep 21.
5
De novo regulation of RD3 synthesis in residual neuroblastoma cells after intensive multi-modal clinical therapy harmonizes disease evolution.强化多模式临床治疗后残余神经母细胞瘤细胞中 RD3 合成的从头调控使疾病进程协调一致。
Sci Rep. 2019 Aug 13;9(1):11766. doi: 10.1038/s41598-019-48034-2.
6
The Prognostic Significance of NEK2 in Hepatocellular Carcinoma: Evidence from a Meta-Analysis and Retrospective Cohort Study.NEK2在肝细胞癌中的预后意义:一项Meta分析和回顾性队列研究的证据
Cell Physiol Biochem. 2018;51(6):2746-2759. doi: 10.1159/000495966. Epub 2018 Dec 12.
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Oncotarget. 2018 Jan 16;9(10):8823-8835. doi: 10.18632/oncotarget.24260. eCollection 2018 Feb 6.
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ALK Protein Expression Is Related to Neuroblastoma Aggressiveness But Is Not Independent Prognostic Factor.ALK 蛋白表达与神经母细胞瘤侵袭性相关,但不是独立的预后因素。
Cancer Res Treat. 2018 Apr;50(2):495-505. doi: 10.4143/crt.2016.577. Epub 2017 May 22.
9
Proliferation and Survival of Embryonic Sympathetic Neuroblasts by MYCN and Activated ALK Signaling.MYCN和活化的ALK信号传导促进胚胎交感神经母细胞的增殖与存活。
J Neurosci. 2016 Oct 5;36(40):10425-10439. doi: 10.1523/JNEUROSCI.0183-16.2016.
10
Factors associated with treatment delay among tuberculosis patients referred from a tertiary hospital in Dhaka City: a cross-sectional study.达卡市一家三级医院转诊的结核病患者治疗延迟相关因素:一项横断面研究。
Public Health Action. 2013 Dec 21;3(4):317-22. doi: 10.5588/pha.13.0067.