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儿童新生血管性青光眼:病例系列及文献复习。

Neovascular Glaucoma in Children: A case series and a review of the literature.

机构信息

Departamento de oftalmología Infantil, 16268Hospital Universitario La Paz, Madrid, Spain.

出版信息

Eur J Ophthalmol. 2022 Nov;32(6):3289-3294. doi: 10.1177/11206721221078678. Epub 2022 Feb 8.

DOI:10.1177/11206721221078678
PMID:35132889
Abstract

PURPOSE

To study the uncommon causes and treatment options for neovascular glaucoma in children.

PATIENTS AND METHODS

A review of the literature on neovascular glaucoma in children was conducted and we present three cases of neovascular glaucoma in children.

RESULTS

We present three cases of neovascular glaucoma: two cases were secondary to a retinal vasoproliferative tumor-one to neurofibromatosis type 1 and the other to exudative retinopathy secondary to mild retinopathy of prematurity-and one case was secondary to a central retina vein occlusion secondary to an optic nerve glioma. Vision in the affected eye was severely impaired in all the children.

CONCLUSION

The diagnosis and treatment of neovascular glaucoma in children is challenging and often a complication of a systemic or late-stage ocular condition. An appropriate diagnosis and estimation of the visual potential are essential to determine the correct treatment, especially in young children.

摘要

目的

研究儿童新生血管性青光眼的罕见病因和治疗选择。

患者与方法

对儿童新生血管性青光眼的文献进行了回顾,并介绍了 3 例儿童新生血管性青光眼病例。

结果

我们介绍了 3 例新生血管性青光眼病例:2 例继发于视网膜血管增生性肿瘤,1 例继发于 1 型神经纤维瘤病,另 1 例继发于轻度早产儿视网膜病变的渗出性视网膜病变;1 例继发于视神经胶质瘤的视网膜中央静脉阻塞。所有患儿受累眼的视力均严重受损。

结论

儿童新生血管性青光眼的诊断和治疗具有挑战性,通常是全身或晚期眼部疾病的并发症。为了确定正确的治疗方法,特别是在年幼的儿童中,进行适当的诊断和视力潜力评估至关重要。

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1
Neovascular Glaucoma in Children: A case series and a review of the literature.儿童新生血管性青光眼:病例系列及文献复习。
Eur J Ophthalmol. 2022 Nov;32(6):3289-3294. doi: 10.1177/11206721221078678. Epub 2022 Feb 8.
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Iris neovascularization and neovascular glaucoma in neurofibromatosis type 1: report of 3 cases in children.1 型神经纤维瘤病中的虹膜新生血管和新生血管性青光眼:3 例儿童病例报告。
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Neovascular glaucoma.新生血管性青光眼
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Neovascular glaucoma associated with cilioretinal artery occlusion combined with perfused central retinal vein occlusion.伴有睫状视网膜动脉阻塞合并灌注良好的视网膜中央静脉阻塞的新生血管性青光眼
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Korean J Ophthalmol. 2013 Feb;27(1):64-7. doi: 10.3341/kjo.2013.27.1.64. Epub 2013 Jan 9.
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[Intravitreal bevacizumab for treatment of neovascular glaucoma. Report of 20 cases].玻璃体内注射贝伐单抗治疗新生血管性青光眼。20例报告
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引用本文的文献

1
Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report.4岁女童双侧闭塞性视网膜血管炎首发症状为新生血管性青光眼:一例报告
Biomedicines. 2025 Jan 9;13(1):148. doi: 10.3390/biomedicines13010148.
2
Anterior chamber fluorescein leakage in a child with intraocular pressure elevation and vitreous hemorrhage.一名眼压升高且伴有玻璃体积血的儿童出现前房荧光素渗漏。
Am J Ophthalmol Case Rep. 2023 Sep 28;32:101935. doi: 10.1016/j.ajoc.2023.101935. eCollection 2023 Dec.
3
Retinal vasoproliferative tumour: differential diagnoses and treatment considerations in a paediatric patient.
视网膜血管性增生肿瘤:儿科患者的鉴别诊断和治疗注意事项。
BMJ Case Rep. 2023 Sep 5;16(9):e254859. doi: 10.1136/bcr-2023-254859.