Lanza F L, Smith V, Page-Castell J A, Castell D O
South Med J. 1986 Mar;79(3):327-30. doi: 10.1097/00007611-198603000-00017.
A double-blind, placebo-controlled, randomized crossover study was made of 60 patients with chronic heartburn to test the efficacy of foaming antacid in promoting symptom relief. Heartburn was induced by a meal consisting of chili, black coffee, and a spicy tomato drink mix. Of the 60 patients, 40 (67%) had relief within 15 minutes after taking foaming antacid tablets as compared to only 17 (28%) after taking a placebo. The difference in response was significant (P less than .05). Foaming antacid appears to be an effective therapy for acute postprandial heartburn.
一项针对60名慢性胃灼热患者的双盲、安慰剂对照、随机交叉研究，旨在测试泡沫抗酸剂缓解症状的疗效。胃灼热由包含辣椒、黑咖啡和辣味番茄饮料混合物的一餐引发。60名患者中，40名（67%）在服用泡沫抗酸剂片后15分钟内症状得到缓解，相比之下，服用安慰剂后只有17名（28%）症状缓解。反应差异具有显著性（P小于0.05）。泡沫抗酸剂似乎是治疗急性餐后胃灼热的有效疗法。
