School of New Energy and Materials, Southwest Petroleum University, Chengdu, 610500, China.
Faculty of Geosciences and Environmental Engineering, Southwest Jiaotong University, Sichuan, 610000, China.
Environ Sci Pollut Res Int. 2022 Jun;29(29):44504-44512. doi: 10.1007/s11356-022-18949-x. Epub 2022 Feb 8.
Drug residues, including various antibiotics, are being increasingly detected in aqueous environments. Ofloxacin (OFX) is one such antibiotic that is widely used in the treatment of several bacterial infections; however, chronic exposure to this antibiotic can have adverse impacts on human health. Hence, the identification of an effective OFX degradation method is essential. Thus, in this study, the degradation performance of OFX using potassium ferrate (Fe(VI)) under the influence of different initial concentrations, pH, temperature, and common ions in water was investigated. OFX degradation by Fe(VI) was directly proportional to the concentration of Fe(VI) and temperature and inversely proportional to the pH. Among the common ions in water, Fe and NH could significantly promote the degradation of OFX by Fe(IV), while humic acid (HA) significantly inhibited it. Under the conditions of [Fe(VI)]:[OFX] = 15:1, T = 25℃, and pH = 7.0, the removal efficiency of 8 μM OFX reached more than 90% in 4 min. Seven intermediates were identified by quadrupole time-of-flight tandem ultra-performance liquid chromatography mass spectrometry (Q-TOF LC/MS), and two possible pathways for the degradation of OFX by Fe(VI) were proposed. Overall, the results suggest that advanced oxidation technology using Fe(VI) is effective for treating wastewater containing OFX.
水中环境中越来越多地检测到药物残留，包括各种抗生素。氧氟沙星（OFX）是一种被广泛用于治疗多种细菌感染的抗生素；然而，慢性接触这种抗生素会对人类健康产生不良影响。因此，确定一种有效的 OFX 降解方法至关重要。因此，在这项研究中，研究了高铁酸钾（Fe(VI)）在不同初始浓度、pH 值、温度和水中常见离子的影响下对 OFX 的降解性能。Fe(VI) 对 OFX 的降解与 Fe(VI)浓度、温度成正比，与 pH 值成反比。在水中的常见离子中，Fe 和 NH 可显著促进 Fe(IV)对 OFX 的降解，而腐殖酸（HA）则显著抑制其降解。在 [Fe(VI)]：[OFX] = 15:1、T = 25℃和 pH = 7.0 的条件下，4 分钟内 8 μM OFX 的去除率超过 90%。通过四极杆飞行时间串联超高效液相色谱-质谱（Q-TOF LC/MS）鉴定出 7 种中间体，并提出了 Fe(VI) 降解 OFX 的两种可能途径。总的来说，结果表明，使用 Fe(VI)的高级氧化技术是处理含 OFX 废水的有效方法。
