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患有和不患有疑似肌少症的老年人的患病率、身体特征和跌倒风险。

Prevalence, physical characteristics, and fall risk in older adults with and without possible sarcopenia.

机构信息

Department of Exercise Prescription, Dongshin University, 67, Dongsindae-gil, Naju-si, Jeonnam, 58245, Republic of Korea.

Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, 81, Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

出版信息

Aging Clin Exp Res. 2022 Jun;34(6):1365-1371. doi: 10.1007/s40520-022-02078-z. Epub 2022 Feb 8.

Abstract

BACKGROUND

Recently, the Asian Working Group for Sarcopenia (AWGS) 2019 consensus redefined the sarcopenia including possible sarcopenia, sarcopenia and severe sarcopenia and grip strength cutoff value by sex.

AIMS

This study aimed to assess the prevalence, physical characteristics, physical fitness, and fall risk in older adults living in local communities, with possible sarcopenia using the diagnostic criteria suggested by the AWGS 2WG.

METHODS

A total of 431 participants (123 men and 308 women) aged 65-97 years were enrolled in this study. Based on the diagnostic criteria of possible sarcopenia suggested by AWGS 2, study participants were divided into normal and possible sarcopenia (grip strength: < 28 kg and < 18 kg for men and women, respectively) groups. Independent t-tests and logistic regression analyses were conducted to compare the differences between the two groups.

RESULTS

The possible prevalence of sarcopenia was 23.7%. Possible sarcopenia was present in older adults with lower weight, body mass index (BMI), skeletal muscle mass, and fat-free mass (P < 0.05) than those in the normal group. Older men with possible sarcopenia had poorer upper and lower body strength, aerobic endurance, lower body flexibility, agility and dynamic balance, and a higher fall risk than those in the normal group (P < 0.05). Older women with possible sarcopenia had a 2.5-fold and 3.3-fold higher fall risk than women in the normal group in both an unadjusted model (P = 0.001) and in a model adjusted for age and BMI (P < 0.001). However, there were no significant differences in fall risk among older men.

CONCLUSION

The diagnostic criteria suggested by AWGS 2 may be highly useful for screening for declining physical function.

摘要

背景

最近,亚洲肌肉减少症工作组(AWGS)2019 共识重新定义了肌肉减少症,包括可能的肌肉减少症、肌肉减少症和严重肌肉减少症以及按性别划分的握力截断值。

目的

本研究旨在使用 AWGS 2WG 建议的诊断标准评估居住在当地社区的老年人中可能的肌肉减少症的患病率、身体特征、身体适应性和跌倒风险。

方法

本研究共纳入 431 名年龄在 65-97 岁的参与者(男性 123 名,女性 308 名)。根据 AWGS 2 建议的可能肌肉减少症的诊断标准,将研究参与者分为正常和可能的肌肉减少症(握力:男性<28kg,女性<18kg)组。采用独立 t 检验和逻辑回归分析比较两组间的差异。

结果

可能的肌肉减少症患病率为 23.7%。与正常组相比,可能的肌肉减少症患者体重、体质指数(BMI)、骨骼肌量和去脂体重较低(P<0.05)。患有可能的肌肉减少症的老年男性上下肢力量、有氧耐力、下肢柔韧性、敏捷性和动态平衡较差,跌倒风险较高(P<0.05)。与正常组相比,患有可能的肌肉减少症的老年女性在未调整模型(P=0.001)和调整年龄和 BMI 的模型(P<0.001)中,跌倒风险分别高出 2.5 倍和 3.3 倍。然而,老年男性的跌倒风险没有显著差异。

结论

AWGS 2 建议的诊断标准可能非常有助于筛选身体功能下降的人群。

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