Grosman Yacov, Kalichman Leonid
Department of Physical Therapy, Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel.
Department of Physical Therapy, Meuhedet Health Maintenance Organization, Rosh Haayin 4809139, Israel.
Int J Environ Res Public Health. 2025 Apr 2;22(4):547. doi: 10.3390/ijerph22040547.
The global aging population faces a growing prevalence of sarcopenia and musculoskeletal (MSK) pain, two interrelated conditions that diminish physical function, quality of life, and independence in older adults. Sarcopenia, characterized by the loss of muscle strength, mass, and function, often coexists with MSK pain, with emerging evidence suggesting that each condition may contribute to the progression of the other. This perspective explores the bidirectional relationship between sarcopenia and MSK pain, highlighting shared mechanisms, including inactivity, cellular aging, chronic inflammation, gender-related hormonal changes, and psychosocial factors such as depression and social isolation, which underlie the mutual exacerbation between conditions. Through a multidisciplinary framework, the article emphasizes integrating care across specialties to address these interconnected conditions. Practical approaches, including comprehensive screening protocols, tailored resistance exercise, and nutritional support, are discussed alongside innovative hybrid care models combining in-person and telemedicine systems to enhance accessibility and continuity of care. A call to action is presented for clinicians, policymakers, and researchers to adopt collaborative strategies, prioritize investment in integrated healthcare, and bridge critical knowledge gaps. By reframing care delivery and advancing multidisciplinary efforts, this perspective aims to effectively address the complex challenges posed by the intersection of sarcopenia and MSK pain in older adults.
全球老龄化人口面临着肌肉减少症和肌肉骨骼疼痛患病率不断上升的问题，这两种相互关联的状况会削弱老年人的身体功能、生活质量和独立性。肌肉减少症的特征是肌肉力量、质量和功能丧失，它常与肌肉骨骼疼痛并存，新出现的证据表明，每种状况可能都会促使另一种状况的发展。本文探讨了肌肉减少症与肌肉骨骼疼痛之间的双向关系，强调了共同的机制，包括缺乏运动、细胞衰老、慢性炎症、与性别相关的激素变化以及抑郁和社会隔离等心理社会因素，这些因素是这两种状况相互加剧的基础。通过一个多学科框架，本文强调跨专业整合护理以应对这些相互关联的状况。文章讨论了一些实用方法，包括全面的筛查方案、量身定制的阻力训练和营养支持，同时还讨论了结合面对面和远程医疗系统的创新混合护理模式，以提高护理的可及性和连续性。文章呼吁临床医生、政策制定者和研究人员采取合作策略，优先投资综合医疗保健，并弥合关键的知识差距。通过重新构建护理服务并推进多学科努力，本文旨在有效应对老年人肌肉减少症与肌肉骨骼疼痛交叉所带来的复杂挑战。
